Protein Alignment Cad96Cb and Pcdhb5

DIOPT Version :9

• Sequence 1: NP_001287524.1
• Gene: Cad96Cb / 43033
• FlyBaseID: FBgn0039294
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001108074.2
• Gene: Pcdhb5 / 291654
• RGDID: 1304665
• Length: 797
• Species: Rattus norvegicus
• Alignment Length: 732
• Identity: 178/732 - (24%)
• Similarity: 287/732 - (39%)
• Gaps: 216/732 - (29%)

  Fly    41 SFLA--TEDLAVGSIIGKL-----RINGD-------ANAETGDINLSLREK-------------- 77
            ||:|  .:||.:|:  |:|     |:..|       .:.:|||  |.||||
  Rat    42 SFVAHLAKDLGLGA--GELAARSARVVSDFDNQQFMVDPDTGD--LLLREKLDREELCGSVDPCV 102

  Fly    78 -------NAPVEIHPG---------------TKELALSV-ELDKEGVRGPSS------IYVNVIC 113
                   ..||:...|               .|||.|.: |..:.|.|.|.:      :..|.:.
  Rat   103 MHFQVFLEKPVQFFQGELLIQDINDNSPEFPDKELLLKIPENSQPGTRFPLNLAQDLDVGSNGLQ 167

  Fly   114 IRRHSTDPSFVI----------------------------------------P------VNVRVT 132
            ..|.||:|.|.:                                        |      |.:.:.
  Rat   168 EYRVSTNPHFHVLTRNNSEGKKYPELVQDRALDREEQAELSLTLMALDGRSPPRSGTALVRILIM 232

  Fly   133 DVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQ---FL 194
            |:|||||:::.:||.:.:.|...|.:.||. ..|.||| .|.|.:|.|.:...  |:.:|   .:
  Rat   233 DINDNAPEFVNSPYEVQVPESCPPDSPILT-VLAPDAD-AGNFGSVSYGLFQA--SDEIQKTFSI 293

  Fly   195 NPLEGTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSAEIP 259
            |.:.|.:.|||.||:|:.:::.|::.|.|.|........::.|:  |.:|..|:....|.::.:|
  Rat   294 NEVTGEIRLKKELDFEKTESYRVEIEATDGGGLSGKGSVVIEVL--DVNDNAPELTISSLTSSVP 356

  Fly   260 ADGRPGELRMRPEPLKAV----DQDEG-----ICAPIQYTIVQSQDAKYFRIHPHNGAISLLTPI 315
            .:.        ||.:.|:    |:|.|     ||:        ..|...|.:.|
  Rat   357 ENA--------PETVVAIIRIRDRDSGDNGKMICS--------ISDHVPFTLKP----------- 394

  Fly   316 GYADVANGATLVVKATQIDNPDR--YALT-----------TVQLTRPGSHSDL--STLAFVQKRF 365
               ...|..|||.:.. :|...|  |.:|           |.|.|.....||:  :..||.|..:
  Rat   395 ---SYKNFYTLVTERA-LDRESRAEYNITISVSDQGTPRLTTQHTITVQVSDINDNAPAFTQTSY 455

  Fly   366 VMRIREDTAVGNRI--LALPTNKPGK--HLKYVIPDPVNSQFFSVGSL-------GELVLAKPLD 419
            .|.:.|:.:....|  ::...:..|.  |:.|.:..|.:.| .::.||       |:|...:.||
  Rat   456 TMFVHENNSPALHIGTISATDSDSGSNAHITYSLLPPYDPQ-LALDSLISINPDNGQLFALRALD 519

  Fly   420 YEKMTKHEFQVLATDG---MTNSTAELTLEVIDVNDWEPRFRETHYEFMVPKSSLQSRADSFEGV 481
            ||.:...||:|.||||   ..:|.|.:.:.|:|.||..|...........|.:.|..|| :..|.
  Rat   520 YEALQAFEFRVAATDGGSPALSSQALVRVMVLDDNDNAPFVLYPLQNASAPYTELLPRA-AEPGY 583

  Fly   482 LIGKVEAADGDRNDKLELS---LRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVH-LIAIATDTG 542
            ||.||.|.|.|......||   |:....|||.: ...|..:|..:|.|..:...| |:.:..|.|
  Rat   584 LITKVVAVDRDSGQNSWLSFQLLKSTEPGLFSV-WAHNGEVRTTRLLSERDVPKHRLLLVVKDNG 647

  Fly   543 VPPRSTSVPVSVTM-EGLT------------LARSGWNSNMLGMF-----GMIMGLFLMIIVALS 589
            .||||.|:.:.|.: :|.:            .|:.|  :::|.::     ..:..|||:.::
  Rat   648 EPPRSASITLQVVLVDGFSQPYLPLPEVARDSAKDG--ADLLTLYLVIALASVSSLFLLSVL--- 707

  Fly   590 CYI-VRSKKQGKSASSG 605
            .:: ||..::.::||.|
  Rat   708 LFVGVRLCRRARAASLG 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	36/191 (19%)
		Cadherin_repeat	145..244	CDD:206637	30/101 (30%)
		Cadherin_repeat	253..347	CDD:206637	23/115 (20%)
		Cadherin_repeat	365..452	CDD:206637	27/100 (27%)
		Cadherin_repeat	461..555	CDD:206637	31/97 (32%)
Pcdhb5	NP_001108074.2	Cadherin_2	29..111	CDD:400525	18/72 (25%)
		Cadherin_repeat	139..237	CDD:206637	15/97 (15%)
		Cadherin_repeat	245..342	CDD:206637	30/102 (29%)
		Cadherin_repeat	354..446	CDD:206637	25/122 (20%)
		Cadherin_repeat	454..556	CDD:206637	28/102 (27%)
		Cadherin_repeat	570..663	CDD:206637	32/94 (34%)
		Cadherin_C_2	687..769	CDD:406805	9/41 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4545
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050