Protein Alignment Cad96Cb and pcdh8

DIOPT Version :9

• Sequence 1: NP_001287524.1
• Gene: Cad96Cb / 43033
• FlyBaseID: FBgn0039294
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_002938086.2
• Gene: pcdh8 / 100485587
• XenbaseID: XB-GENE-484517
• Length: 1002
• Species: Xenopus tropicalis
• Alignment Length: 767
• Identity: 161/767 - (20%)
• Similarity: 292/767 - (38%)
• Gaps: 224/767 - (29%)

  Fly    11 AILSLCWFNKATLGAILD-SRCYLEGGGSAESFLATEDLAVGSIIG----KLRINGDANAETGDI 70
            |:..||      ||.::. .||      ....:...|:...|::||    .|.:.|:     |..
 Frog    10 ALRLLC------LGMLVSVCRC------KTVRYRTYEEDEPGTVIGTLAEDLHLEGE-----GTF 57

  Fly    71 NLSLREKNAPVEIHPGTKELALSVELDKEGVRGPS---SIYVNVICIRRHSTDPSFVIPVNVRVT 132
            .|..:..|:.:.:.....:|::...:|:|.:...|   ::.::|:.:.:....   :|.|.|.|.
 Frog    58 RLMKQFNNSLIHVRESDGQLSIGERIDRERICKQSPHCTLALDVVSLAKEQFK---LIHVEVEVR 119

  Fly   133 DVNDNAPQWIGTPYTLTLSEVTVPGTRI-LQGARAEDADQPGPFSTVEYQV-LPGPYSEYVQFLN 195
            |:|||:|::......:.:||....|||| |..|..||.   |..|...:|: :...:|..||  .
 Frog   120 DINDNSPRFPSAEIPVEVSESATVGTRIPLDIATDEDV---GVNSIQSFQISVNSHFSIDVQ--T 179

  Fly   196 PLEGT----LVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPKFQRESYSA 256
            ..:|.    |||.|.||.|....:|::|.|.|.|:|.|....::.|.:.|.:|.:|.|:|.:.:.
 Frog   180 RADGVKYADLVLMKELDRESQSAYTLELLAMDGGSPSRSGTAMVNVRVLDFNDNSPVFERSAVTV 244

  Fly   257 EIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTI---VQSQDAKYFRIHPHNGAISL------- 311
            |:..|...|.|.:   .|.|||.|||:...|.|..   |..:..:.|:|.|.:|.::|
 Frog   245 ELMEDAPVGYLLL---DLNAVDPDEGVNGEIIYGFSPQVPQEVRQLFKIDPKSGRLTLEGQVDFE 306

  Fly   312 ----------------------------------------LTPI-----GYADVANGAT------ 325
                                                    :||:     |.|.:...|.
 Frog   307 SKQTYEFDVQAQDMGPNPLAATCKVIVHVIDVNDNAPVISITPLTSISAGVAYITEAAARESFVA 371

  Fly   326 -----------------------------------LVVKATQIDNP--DRYALTTVQLTRPGSHS 353
                                               ::|..:.:|..  ..|.||.|.       .
 Frog   372 LISTTDRDSGQNGQVHCTLYGHEHFRLQQAYEDSYMIVTTSALDREKISEYNLTVVA-------E 429

  Fly   354 DLSTLAF-VQKRFVMRIREDTAVGN---------RILALPTNKPGKHLKYVI---PD-------- 397
            ||.:..| ..|::.:|:.::.  .|         .:..|..|.||.::..|:   ||
 Frog   430 DLGSPPFKTVKQYTIRVSDEN--DNAPVFAKPVYEVSVLENNAPGAYITTVVARDPDFGHNGKVI 492

  Fly   398 -----------PVNSQFFSVGSLGELVLAKPLDYEKMTKHEFQVLATDG---MTNSTAELTLEVI 448
                       |:::......:.|.:...:..::|.:.:.:.::.|:||   ...|:|.:.::::
 Frog   493 YRLVETEVMGAPISTYVSLDPATGAVYALRTFNHEILKQLDLRIQASDGGSPQLTSSAIIKVKIV 557

  Fly   449 DVND-----WEPRFRETHYEFMVPKSSLQSRADSFEGVLIGKVEAADGDR--NDKLELSLRGQHA 506
            |.||     .:|.......|.:||     |||.  .|.|:.:::|.|.|.  |.:|..||.....
 Frog   558 DQNDNAPVIIQPALSNGSAEVVVP-----SRAP--HGFLVTQIKAKDADEGVNAELSYSLTEDGR 615

  Fly   507 GLFEIDS-TGNIYMRPEQLQSLNESTVHLIAI---ATDTGVPPRSTSVPVSVTMEGLT------- 560
            .||.|:. ||.:::    :..::|:..|:..:   .:|:|.||.|::..::..:...|
 Frog   616 NLFTINKVTGEVFL----VADVSEAVGHVFRVTVSVSDSGRPPLSSTATITFLVTSATPPINPEL 676

  Fly   561 LARSGWNSNM------LGMFGMIMG-----LFLMIIVALSCYIVRSKKQGKS 601
            :..|.|...:      |.:..::.|     |..:|.:|.:|...|.:.:|.|
 Frog   677 MQPSSWEEKVSRWDVPLIVIIVLAGSCTLLLAAIITIATTCNKRRKENKGDS 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	20/97 (21%)
		Cadherin_repeat	145..244	CDD:206637	33/104 (32%)
		Cadherin_repeat	253..347	CDD:206637	30/191 (16%)
		Cadherin_repeat	365..452	CDD:206637	18/120 (15%)
		Cadherin_repeat	461..555	CDD:206637	27/99 (27%)
pcdh8	XP_002938086.2	Cadherin_2	27..102	CDD:400525	13/79 (16%)
		Cadherin_repeat	132..233	CDD:206637	33/105 (31%)
		Cadherin_repeat	243..341	CDD:206637	19/100 (19%)
		Cadherin_repeat	357..452	CDD:206637	13/103 (13%)
		Cadherin_repeat	460..562	CDD:206637	17/101 (17%)
		Cadherin_repeat	577..666	CDD:206637	27/99 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4624
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050