DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cad96Cb and LOC100485160

DIOPT Version :9

Sequence 1:	NP_001287524.1	Gene:	Cad96Cb / 43033	FlyBaseID:	FBgn0039294	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	XP_031748020.1	Gene:	LOC100485160 / 100485160	-ID:	-	Length:	856	Species:	Xenopus tropicalis

Alignment Length:	612	Identity:	134/612 - (21%)
Similarity:	232/612 - (37%)	Gaps:	140/612 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIGKLRINGDANAETGDIN 71
            :|:|.:|.                  .....|..:|...|:...|:.||.|:.|   :.|:..:.
Frog    12 FIFYTLLE------------------FTASASELTFYIPEEQNEGTYIGSLKTN---SLESSPLQ 55

  Fly    72 LSLREKNAPVEIHPGTKEL-ALSVELDKEGVRGPSSI---YVNV---ICIRRHSTDPSFVIPVNV 129
            ..|...:....:...|.:| ..:.:||:|.:....::   :|.:   :..:.||.    :..:.:
Frog    56 YKLLPPSIYFHLDKQTGDLYTTAFKLDREHLCPQDTLNQCFVEIDAFVSSQEHSE----IAKIKI 116

  Fly   130 RVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFL 194
            .:.|:||:||.:.....|:::.|.|..||.......|.|.|             .|..|..:..|
Frog   117 FILDINDHAPFFTDRIITISVQEDTAVGTIFPIDHSASDPD-------------AGQNSILLYHL 168

  Fly   195 NPLEG-----------TLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQNPK 248
            |.::.           :|.|::.||:|....:.:.|.|.|:|.||.....|:.|.|||.:|..|.
Frog   169 NSIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGSALIIVQITDVNDNCPV 233

  Fly   249 F---------QRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTI---VQSQDAKYFR 301
            |         ||.|            .:......|:|||:|.|..:.|||..   |.::..|.|.
Frog   234 FLTSNMFIILQRNS------------SVNSTVTQLEAVDEDTGENSIIQYVYSNRVPAESKKLFH 286

  Fly   302 IHPHNGAISLLTPIGYADVANGATLVVKATQIDNPDRYALTTVQLTRPGSHSDLSTLAFV----- 361
            :....|.:.|..||                ..|:|:.:.||.:.: .||....::|:...
Frog   287 LESMTGILRLAAPI----------------PEDSPNNHKLTVLAI-GPGCAPAVATVKLAIQELK 334

  Fly   362 --QKRFVMR-----------IREDTAVGNRILALPTNKPGKHLKYVIPDPV--NSQFFSVGSLGE 411
              :.|...|           ::||..:...|..|..    |...|.|..||  |........:.|
Frog   335 RKEPRMEFRVIGAQGEEGVSVKEDVPINTIIAILEI----KDTDYSILRPVYINGTIPFALKVSE 395

  Fly   412 -------LVLAKPLDYEKMTKHEFQVLAT---DGMTNSTAELTLEVIDVNDWEPRFRETHYEFMV 466
                   |:.:..||:|...|:..|||..   |.:....|.|.:::.||||..|:|.::..|..|
Frog   396 NSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVSV 460

  Fly   467 PKSSLQSRADSFEGVLIGKVEAADGD--RNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNE 529
            .:       ::..|.:|.::.|.|.|  .|..::.|...:....|.||::..|...........:
Frog   461 EE-------NNSPGAVILELSAFDRDSGSNGIIDYSFGAELPMEFFIDASHGILTASVSFDREQK 518

  Fly   530 STVHLIAIATDTGVPPRSTSVPVSVTM 556
            ::..:|.:|:|.|.|.::.|..|.:|:
Frog   519 TSYTVIVLASDHGSPAQNGSCTVIITI 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	18/97 (19%)
		Cadherin_repeat	145..244	CDD:206637	28/109 (26%)
		Cadherin_repeat	253..347	CDD:206637	21/96 (22%)
		Cadherin_repeat	365..452	CDD:206637	25/109 (23%)
		Cadherin_repeat	461..555	CDD:206637	20/95 (21%)
LOC100485160	XP_031748020.1	Cadherin_repeat	26..124	CDD:206637	19/104 (18%)
		Cadherin_repeat	132..230	CDD:206637	28/110 (25%)
		Cadherin_repeat	246..331	CDD:206637	24/113 (21%)
		Cadherin_repeat	353..447	CDD:206637	25/97 (26%)
		Cadherin_repeat	455..551	CDD:206637	21/98 (21%)
		Cadherin_repeat	559..652	CDD:206637
		Cadherin_repeat	665..756	CDD:206637
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4624
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050