Protein Alignment Cad96Cb and pcdhb

DIOPT Version :9

• Sequence 1: NP_001287524.1
• Gene: Cad96Cb / 43033
• FlyBaseID: FBgn0039294
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_002664314.3
• Gene: pcdhb / 100333352
• ZFINID: ZDB-GENE-020731-3
• Length: 728
• Species: Danio rerio
• Alignment Length: 706
• Identity: 173/706 - (24%)
• Similarity: 285/706 - (40%)
• Gaps: 137/706 - (19%)

  Fly    62 DANAETGDINLSLREKNAPVEIH---PGTK--ELALSVELDKEGVRGPSSIYVNVICIRRHSTDP 121
            |..|.|.........::..|:||   .|||  :|.|...||:|    ..::: |:|........|
Zfish    73 DVGANTVKTYKLSENEHFTVDIHSGSDGTKYVDLVLMKALDRE----DKAVH-NLILTAIDGGVP 132

  Fly   122 --SFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLP 184
              |....:.|||.|.||||||:....|:|.:||.:..||.::: ..|.|||: ||.:.:.|...
Zfish   133 ARSGTASIIVRVQDTNDNAPQFDQALYSLNISENSPAGTVVVK-LNATDADE-GPNADLTYSFT- 194

  Fly   185 GPY-SEYVQFLNPLE---GTLVLKKALDYEQLQNFTVKLRAQDQGTPPRHSDTLLRVVITDADDQ 245
             .| ||..|.:..|:   |.:.:|..:|||.::.|.:.:.|:|.|..|....:.:.|.:||.:|.
Zfish   195 -LYTSEKTQEMFSLDSNTGEIAVKGTIDYEDMKIFEMFVEAKDNGPVPLSGQSRVSVYVTDMNDN 258

  Fly   246 NPKFQRESYSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQDAKYFRIHPHNGAIS 310
            .|:...:|..                   ..||::..:.:.|....|..:|.      ..||.::
Zfish   259 YPEITIKSLK-------------------NTVDENIPVGSVIALVGVSDRDT------GDNGKVN 298

  Fly   311 LLTPIGYADVANGAT------LVVKATQIDNPDRYALTTVQLTRPGSH--SDLSTLA-------- 359
            |........:.|.::      ||.|....:....|.:|.| :|..|:.  ||..|:.
Zfish   299 LTMNRALPFLLNQSSDHLYELLVSKPLDREVVPEYEITLV-VTDKGNPPLSDNETITVHLLDVND 362

  Fly   360 ----FVQKRFVMRIREDTAVG---NRILAL-PTNKPGKHLKYV-----IPDPVNSQFFSVG-SLG 410
                |.|..:.:.::|:.|.|   ..|.|: |.....::|.|.     |.:...|..||:. ..|
Zfish   363 NAPQFPQTFYTIPVKENNAPGALLGSITAIDPDLNENQYLVYFIIEREIANTSMSMLFSINPENG 427

  Fly   411 ELVLAKPLDYEKMTKHEFQVLATD-GMTNSTAELTLEVI--DVNDWEP------RFRETHYEFMV 466
            .|...|..|||......|.:.|.| |:...::.:|:.:|  |.||..|      |.:.:..:..:
Zfish   428 NLYALKTFDYEIEKDFLFHIEARDSGVPPLSSNVTVHIIIMDQNDNTPLIVSPWRAQGSEVKETI 492

  Fly   467 PKSSLQSRADSFEGVLIGKVEAADGD--RNDKLELS-LRGQHAGLFEIDS-TGNIYMRPEQLQSL 527
            |:|       :.:|.||.||.|.|.|  .|.::... |:...|.||.:|. .|.|  |..::.|.
Zfish   493 PRS-------TDKGTLIAKVIAIDSDSVHNSRITYQFLQNTDATLFSLDQYNGEI--RTMRMFSY 548

  Fly   528 NES-TVHLIAIATDTGVPPRSTSVPVSVTMEGLTLAR-----------SGWNSNM---LGMFGMI 577
            .:| ...|:.||.|.|.|..|.:|.:.::.....|..           |..|..:   ||....:
Zfish   549 RDSRDQRLVVIAKDNGEPALSATVTIKLSTVETALKTYTEVPLEYDIFSDLNLYLVIGLGSVSFL 613

  Fly   578 MGLFLMIIVALSCYIVRSKKQGKSASSGLGLGRNRVHSQAHSSVSSANLVTHEKLAGNGNGNGAS 642
            :.:.:::.:.|.|   :..|..|:|..    .||.|.|:.:|:::.:.||:          |.|.
Zfish   614 LLITILVTIVLKC---QKAKPSKAAPP----SRNSVISERNSTIADSTLVS----------NDAY 661

  Fly   643 VTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMAL----GSSAALLERERE 694
            ..|   ..|.....|.:.:..|:..|..::.|....|..|    .|:|:.|:...|
Zfish   662 WYS---LFLAETRKGKLVVRQPVPKGARYIVSSIPRSTGLTETSDSAASTLQTWEE 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Cb	NP_001287524.1	Cadherin_repeat	46..137	CDD:206637	23/81 (28%)
		Cadherin_repeat	145..244	CDD:206637	31/102 (30%)
		Cadherin_repeat	253..347	CDD:206637	16/99 (16%)
		Cadherin_repeat	365..452	CDD:206637	25/99 (25%)
		Cadherin_repeat	461..555	CDD:206637	29/98 (30%)
pcdhb	XP_002664314.3	Cadherin_repeat	50..150	CDD:206637	23/81 (28%)
		Cadherin_repeat	159..258	CDD:206637	31/102 (30%)
		Cadherin_repeat	270..363	CDD:206637	20/99 (20%)
		Cadherin_repeat	372..473	CDD:206637	26/100 (26%)
		Cadherin_repeat	491..576	CDD:206637	29/93 (31%)
		Cadherin_C_2	598..>640	CDD:318652	8/48 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4620
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.050