Protein Alignment CG31103 and SV2B

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 125/589 - (21%)
• Similarity: 231/589 - (39%)
• Gaps: 133/589 - (22%)

  Fly    17 YDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGIF 81
            |:.::::.|:|:.||:|..|.||..:........:|..:.:::.:...:.::||::......|:.
Human    95 YETIMDECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMM 159

  Fly    82 LSTYIWGYISDDIGRRRVL-----LYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAAL 141
            ...:|.|.::|.:||:|||     :..:|||     :..||.....|....|:.||.:|.....:
Human   160 AGAFILGGLADKLGRKRVLSMSLAVNASFAS-----LSSFVQGYGAFLFCRLISGIGIGGALPIV 219

  Fly   142 YAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSS-NWAITMG-DFVFRPWRLLLLVSL 204
            :||.|||.....|...:::..:|.....:|..|.||.::.. .|..:|| ::.|..||:.::|..
Human   220 FAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCA 284

  Fly   205 LPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFN-RGKSIQQVLSCDEFT---LKSEDP 265
            ||..:..:.|.:.||||:|||...|::||...:..:...| |.|...:.:    ||   :|:...
Human   285 LPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKV----FTVSNIKTPKQ 345

  Fly   266 VGENL-LGESQGC----------GILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLW 319
            :.|.: :..|.|.          .|..::....:.....|:..|.::..:..|.|.||..|:.:|
Human   346 MDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVW 410

  Fly   320 FPEIVNRSSGAENNS------------STVCEILSVPVEQPN----------------VTETL-- 354
            ||:::......|..|            :|:...:...:.|..                ..:|.
Human   411 FPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFD 475

  Fly   355 DC--TDPISSKTYIDNLVV---------------------------------------------- 371
            :|  .|..|:.||..|..:
Human   476 ECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYL 540

  Fly   372 -----GFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGL 431
                 ..:.|.|..|..|:::.:||..::..::.::.:....|.|..|.:.::...||:.   |.
Human   541 VSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFC---GT 602

  Fly   432 SISI--MIGAI-VDLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFT-CTLIV 492
            ||:.  .:..| |:|.||:.|:.|......|.:.|.|..            ||.||.|. .|.:|
Human   603 SIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILG------------NTIFASFVGITKVV 655

  Fly   493 CIVI 496
            .|::
Human   656 PILL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	114/553 (21%)
		MFS	34..>189	CDD:119392	37/160 (23%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	125/589 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920