Protein Alignment CG31103 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 114/547 - (20%)
• Similarity: 196/547 - (35%)
• Gaps: 179/547 - (32%)

  Fly    12 PNVWDYDMVLEKIGYGKTQ-----WVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGV 71
            |..|:.|.::: .|...|.     |:.           ..|::...|......|..||.:....:
Human   217 PVPWNLDSIIQ-FGLNDTDTCQDGWIY-----------PDAKKRSLINEFDLVCGMETKKDTAQI 269

  Fly    72 MMAASVTGIFLSTYIWGYISDDIGRRRVLL----------YGNFASNALQFVLMFVTSVWLFNII 126
            |..|   |:.:.:.|:..|:|.:||...:|          :|....|:....|.|     .|.|.
Human   270 MFMA---GLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLYLFF-----RFGIS 326

  Fly   127 NLLVGISVGAVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDF 191
            ..:||.::.::|.|     :|:.:..|||.||.....|.:|.|:.:...|:.:
Human   327 QSVVGYAISSISLA-----TEWLVGEHRAHAIILGHCFFAVGAVLLTGIAYSL------------ 374

  Fly   192 VFRP-WRLLLLVSLLPGFIGGLILLYY-------PESPKFLLSQEKNNEAIEAVAWISKFNRGKS 248
               | |:||.||       ||::::.:       ||||::|:.:.|..||.:.:.:.:..|: |:
Human   375 ---PHWQLLFLV-------GGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNK-KT 428

  Fly   249 IQQVLSCDEFTLKSEDPVGENLLGESQGCGIL--SKICRATIPLFHKPHGFNFILCNLAL----- 306
            |.                 .|||.|.|    |  .|:.||::..|.|    |..||.:.|
Human   429 IP-----------------SNLLDELQ----LPRKKVTRASVLDFCK----NRQLCKVTLVMSCV 468

  Fly   307 -FGMFFSSNGMQLWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLV 370
             |.:.::...:.|...|:    ..:.:....|..|:.||..       |.|.
Human   469 WFTVSYTYFTLSLRMREL----GVSVHFRHVVPSIMEVPAR-------LCCI------------- 509

  Fly   371 VGFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTG------------------ 417
                         .:|..:|||..|...|..|.:..:||.|:  |.|
Human   510 -------------FLLQQIGRKWSLAVTLLQAIIWCLLLLFL--PEGEDGLRLKWPRCPATELKS 559

  Fly   418 --VLVLFCLYILLPGLSISIMIGAIVDLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQ---- 476
              :|||......| ..::::......:|:||.||:..         ||:::..::.|.:|.
Human   560 MTILVLMLREFSL-AATVTVFFLYTAELLPTVLRATG---------LGLVSLASVAGAILSLTII 614

  Fly   477 PYCNTTFAMFTCTL--IVCIVIVHYLP 501
            ....:...:|.|.:  ||...:...||
Human   615 SQTPSLLPIFLCCVLAIVAFSLSSLLP 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	103/496 (21%)
		MFS	34..>189	CDD:119392	34/164 (21%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	114/547 (21%)
		MFS	270..641	CDD:119392	101/480 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840