Protein Alignment CG31103 and Sv2c

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_083486.1
• Gene: Sv2c / 75209
• MGIID: 1922459
• Length: 727
• Species: Mus musculus
• Alignment Length: 593
• Identity: 123/593 - (20%)
• Similarity: 226/593 - (38%)
• Gaps: 136/593 - (22%)

  Fly    17 YDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGIF 81
            |::::::.|:|:.||.|..|.|:..:........:..::.:::.:.....:..|.:.:....|:.
Mouse   138 YELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMM 202

  Fly    82 LSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYLS 146
            :..:.||.::|.:||::.||.....:....|:..||.....|.:..||.|..:|.....:::|.:
Mouse   203 VGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLVCRLLSGFGIGGAIPTVFSYFA 267

  Fly   147 EFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSS-NWAITMGD-FVFRPWRLLLLVSLLPGFI 209
            |......|...:::..||..:..||..|.||.::.. .|:.:||. :.|..||:.::|..||...
Mouse   268 EVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVS 332

  Fly   210 GGLILLYYPESPKFLLSQEKNNEA-----------------IEAVAWISKFNRGKSIQQVLSCDE 257
            ..:.|.:.||||:|||...|::||                 .|.|..::|....|.|.:::..:.
Mouse   333 SVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIES 397

  Fly   258 FTLKSEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPE 322
            .|..........:..|..|..:....|      |:.|...|.|...:..|.:.|...|:.:|||:
Mouse   398 DTGTWYRRCFVRIRTELYGIWLTFMRC------FNYPVRENTIKLTIVWFTLSFGYYGLSVWFPD 456

  Fly   323 IVNRSSGAEN---------------------------------------------------NSST 336
            ::......|.                                                   .|.|
Mouse   457 VIKHLQSDEYALLTRNVQKDKYANFSINFTMENQIHTGMEYENGRFLGVKFKSVTFKDSVFKSCT 521

  Fly   337 VCEILSVPVEQPNVT--ETL-DCTD--P-------------ISSKT---------------YIDN 368
            ..::.||.....|.|  :|| |.||  |             :.:||               |..|
Mouse   522 FDDVTSVNTYFKNCTFIDTLFDNTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVN 586

  Fly   369 LVVGFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSI 433
            .:...|.|.|..:..|:::.:||..:|..::.::.:|...|.|..|.:.::.:.|||   .||:|
Mouse   587 FLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLY---NGLTI 648

  Fly   434 SI---MIGAIVDLVPTHLRSKAVSF----CMSLGRLG------IIAATNLMGVMLQPYCNTTFAM 485
            |.   :....|:|.||..|:....|    |.:...||      :::.|..:.::|
Mouse   649 SAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILL---------- 703

  Fly   486 FTCTLIVC 493
             ..|::||
Mouse   704 -ASTVLVC 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	116/561 (21%)
		MFS	34..>189	CDD:119392	30/155 (19%)
Sv2c	NP_083486.1	synapt_SV2	1..727	CDD:130366	123/593 (21%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..128

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920