Protein Alignment CG31103 and SLC22A3

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_068812.1
• Gene: SLC22A3 / 6581
• HGNCID: 10967
• Length: 556
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 110/472 - (23%)
• Similarity: 177/472 - (37%)
• Gaps: 107/472 - (22%)

  Fly    49 QAMSIIVIASQCEF----------ETTQAEKGVMMAASVTGIFLSTYIWGYISDDIGRRRVLLYG 103
            ||.|.||    .||          :.|||   ::....:||.|    ..||.:|..||..:.|..
Human   135 QAHSTIV----SEFDLVCVNAWMLDLTQA---ILNLGFLTGAF----TLGYAADRYGRIVIYLLS 188

  Fly   104 NFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYLSEFNIPRHRAVAINYSTMFVSVT 168
            .........|:.|..:..:|.|...|.|:.........|..::|....:.|.:......||.::.
Human   189 CLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLG 253

  Fly   169 AIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLVSLLPGFIGGLILLYY---PESPKFLLSQEKN 230
            .|.:|..|:.:.:              |:.:.|...||.|   |.||||   ||||::|::::|.
Human   254 IIILPGIAYFIPN--------------WQGIQLAITLPSF---LFLLYYWVVPESPRWLITRKKG 301

  Fly   231 NEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSEDPVGENLLGESQGCGILSKICRATIPLFHKPH 295
            ::|::.:..|:|.| ||.:....|  |.|:..|:....:.|          .:.|.  |...|
Human   302 DKALQILRRIAKCN-GKYLSSNYS--EITVTDEEVSNPSFL----------DLVRT--PQMRK-- 349

  Fly   296 GFNFILCNLALFGMFFSSNGMQLWFPEIVNRSSGAENNSSTVCE--ILSVPVEQPNVTETLDCTD 358
                  |.|.|         |..||            .|:.|.:  ::.:.:
Human   350 ------CTLIL---------MFAWF------------TSAVVYQGLVMRLGI------------- 374

  Fly   359 PISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFC 423
             |....|||..:.|...|.|..:..|.:..|||:....|:..||.::.::..|:  |.|:..|..
Human   375 -IGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFL--PEGIAWLRT 436

  Fly   424 LYILLPGLSISIMIGAIV----DLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFA 484
            ....|..|.|::....:.    :|.||.||:..||.|..|...|.|.|..|:..:...:......
Human   437 TVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLI 501

  Fly   485 MFTCTLIVCIVIVHYLP 501
            :|.....:|..:|..||
Human   502 IFGILASICGGLVMLLP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	105/444 (24%)
		MFS	34..>189	CDD:119392	33/149 (22%)
SLC22A3	NP_068812.1	2A0119	12..528	CDD:273328	110/472 (23%)
		MFS	149..518	CDD:119392	101/452 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840