Protein Alignment CG31103 and SLC22A1

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 113/394 - (28%)
• Similarity: 159/394 - (40%)
• Gaps: 102/394 - (25%)

  Fly    88 GYISDDIGRRRVLLYGNFASNALQFVLMFVT----SVWLFNIINLLVGISVGAVSAALYAYLSEF 148
            ||.:|..||:..|| |....||:..|||..:    |:.||.::..||  |.|...|. |..::||
Human   167 GYFADRFGRKLCLL-GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLV--SKGNWMAG-YTLITEF 227

  Fly   149 -NIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLVSLLPGFIGGL 212
             .....|.|||.|...|          |..||     |:|...:....||.|.|...||.|   |
Human   228 VGSGSRRTVAIMYQMAF----------TVGLV-----ALTGLAYALPHWRWLQLAVSLPTF---L 274

  Fly   213 ILLYY---PESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSEDPVGENLLGES 274
            .||||   ||||::||||::|.|||:.:..|::.| ||    :...|...|..|:.|.|
Human   275 FLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKN-GK----LPPADLKMLSLEEDVTE------ 328

  Fly   275 QGCGILSKICRATIPLFHKP--HGFNFILCNLALFGMFFSSNGMQLWFPEIVNRSS-----GAEN 332
                   |:..:...||..|  ....|||              |.|||.:.|....     ||.:
Human   329 -------KLSPSFADLFRTPRLRKRTFIL--------------MYLWFTDSVLYQGLILHMGATS 372

  Fly   333 NSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVLL- 396
            .:..:..:.|..||.|.                      .|..||.....|.|. |:...|:|.
Human   373 GNLYLDFLYSALVEIPG----------------------AFIALITIDRVGRIY-PMAMSNLLAG 414

  Fly   397 AALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGAIV--DLVPTHLRSKAVSFCMSL 459
            ||..|.......||::.     :::.|:..:  |::|:|.:..:|  :|.||.:|:..|..|.||
Human   415 AACLVMIFISPDLHWLN-----IIIMCVGRM--GITIAIQMICLVNAELYPTFVRNLGVMVCSSL 472

  Fly   460 GRLG 463
            ..:|
Human   473 CDIG 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	79/245 (32%)
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	113/394 (29%)