Protein Alignment CG31103 and Sv2a

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_071313.1
• Gene: Sv2a / 64051
• MGIID: 1927139
• Length: 742
• Species: Mus musculus
• Alignment Length: 584
• Identity: 124/584 - (21%)
• Similarity: 214/584 - (36%)
• Gaps: 152/584 - (26%)

  Fly    17 YDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGIF 81
            |:.:|.:.|:|:.||.|..|.||..:........:..::.:::.:...:.:.||::......|:.
Mouse   152 YETILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMM 216

  Fly    82 LSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYLS 146
            :..::||.::|.:|||:.||.....::...|...||.....|....||.|:.:|.....:::|.|
Mouse   217 VGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFS 281

  Fly   147 EFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSS-NWAITMGD-FVFRPWRLLLLVSLLPGFI 209
            ||.....|...:::..||..:..:|..|.||.::.. .|:..||. :.|..||:.:||...|...
Mouse   282 EFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVF 346

  Fly   210 GGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFN-RGKS-IQQVLSCDEF-TLKSEDPVGE--- 268
            ....|...||||:|.|...|::||...:..:...| |.|. .::|.|.... |:..||.:.|
Mouse   347 AIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQS 411

  Fly   269 --------------NLLGESQGCGILSKICRATIPLFHKPHGFNFILC--------NLALFG--- 308
                          :|.|:..|                     ||:.|        .|.:.|
Mouse   412 DTGTWYQRWGVRALSLGGQVWG---------------------NFLSCFSPEYRRITLMMMGVWF 455

  Fly   309 -MFFSSNGMQLWFPEIVNRSSGAE---------------------------------NNSSTVCE 339
             |.||..|:.:|||:::......:                                 |:......
Mouse   456 TMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLR 520

  Fly   340 ILSVPVEQPNVTETLDCTDPISSKTYIDNL----------------------------------- 369
            :.||..|. ::.|.....|..||.|:..|.
Mouse   521 LKSVSFED-SLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCP 584

  Fly   370 --VVG----------------FAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPT 416
              |.|                .|.|.|..:..|:::.:||..:|..:..::.:|...|.|..|.:
Mouse   585 LDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSES 649

  Fly   417 GVLVLFCLYILLPGLSI---SIMIGAIVDLVPTHLRSKAVSF----CMSLGRLGIIAATNLMGV 473
            .::.|.||:   .|:||   :.:....|:|.|:..|:.|..|    |.....|||...|:.:|:
Mouse   650 AMIALLCLF---GGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGI 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	120/572 (21%)
		MFS	34..>189	CDD:119392	34/155 (22%)
Sv2a	NP_071313.1	synapt_SV2	1..742	CDD:130366	124/584 (21%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..145

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5294
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8715
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860