Protein Alignment CG31103 and SLC22A23

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_054212174.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 718
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 97/474 - (20%)
• Similarity: 172/474 - (36%)
• Gaps: 132/474 - (27%)

  Fly    77 VTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMF------VTSVWLFNIINLLVGISVG 135
            :.|:.....|.|.|:|.:|||.|||:      ::.|:|:|      ..:|.:|:.:....|..:.
Human   261 LVGLIFGYLITGCIADWVGRRPVLLF------SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLA 319

  Fly   136 AVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAI----YVPATAWLVLSSNWAITMGDFVFRPW 196
            .:...|||...|...|..|.:.    ||..|..|:    .:|..|.|.              |.|
Human   320 GIILTLYALRIELCPPGKRFMI----TMVASFVAMAGQFLMPGLAALC--------------RDW 366

  Fly   197 RLLLLVSLLPGFIGGLILLY---YPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEF 258
            ::|..:.:.| |:  |:|||   :|||.::|::.::...|...:...::.||
Human   367 QVLQALIICP-FL--LMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNR------------- 415

  Fly   259 TLKSEDPVGENLLGESQGCGILSKICRATIP-----LFHKPHGFNFILCNLALFGMFFSSNGMQL 318
                .:|.|:               .:..||     |..:|..    :|.:.:.|.      ..|
Human   416 ----MNPEGD---------------IKGVIPELEKELSRRPKK----VCIVKVVGT------RNL 451

  Fly   319 WFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQG 383
            |...:|...:.........|...|:...:..|        |:....|.|........|:......
Human   452 WKNIVVLCVNSLTGYGIHHCFARSMMGHEVKV--------PLLENFYADYYTTASIALVSCLAMC 508

  Fly   384 LILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPG--LSISIMIG-------- 438
            :::..|||:..||..:.:..|:.:|      ..|:|.|...|...|.  |.:.:.:|
Human   509 VVVRFLGRRGGLLLFMILTALASLL------QLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDK 567

  Fly   439 -----AIVDLVPTH-LRSKAVSFCMSL-------GRLGIIAATNLMGVMLQPYCN--------TT 482
                 :||.:..:| :.|.:|.||..:       |.||::.|:...|::..|...        ..
Human   568 FSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLH 632

  Fly   483 FAMFTCTLIVCIVIVHYLP 501
            ..:|.|..::||:.:..||
Human   633 HIIFACCTLICIICILLLP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	56/264 (21%)
SLC22A23	XP_054212174.1	MFS_SLC22A23	192..637	CDD:341002	91/458 (20%)