Protein Alignment CG31103 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 120/489 - (24%)
• Similarity: 193/489 - (39%)
• Gaps: 125/489 - (25%)

  Fly    15 WDYDMVLEKIGYGKT---------QWVLLLVSGLLTITSVAAQQ----AMSIIVIASQCEFETTQ 66
            ||...:|....:|..         .|       |||.......:    :.|...|||:......:
Human    50 WDLAELLPNQSHGNQSAGEDQAFGDW-------LLTANGSEIHKHVHFSSSFTSIASEWFLIANR 107

  Fly    67 AEKGVMMAAS--VTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLM--FVTSVWLFNIIN 127
            :.| |..|:|  .:|:|:....:|.:||..||::|.|.| ||.:.| |.:.  |..|...|.:..
Human   108 SYK-VSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTG-FALDIL-FAIANGFSPSYEFFAVTR 169

  Fly   128 LLVGISVGAVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFV 192
            .|||:..|.:|...:..|:|       .|...|..:..|:..::     :.|..:.:|: :|.|:
Human   170 FLVGMMNGGMSLVAFVLLNE-------CVGTAYWALAGSIGGLF-----FAVGIAQYAL-LGYFI 221

  Fly   193 FRPWRLLLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDE 257
             |.||.|.::..|.|.:..|:.|:.||||::|.||.:.:||.||:..|:|.||      .|.|
Human   222 -RSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNR------KLKC-- 277

  Fly   258 FTLKSEDPVGENLLGESQGCGILSKICRAT---IPLFH----KPHG----FNFILCNLALFGMFF 311
             |.....|.              ::.||.|   :.||.    ..|.    |.:.:|:|..:|:..
Human   278 -TFSLTHPA--------------NRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTL 327

  Fly   312 SSNGMQLWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFL 376
            |:..:        ..|..|....|.:.||.|.|:          |...|:.|.:
Human   328 SAGDL--------GGSIYANLALSGLIEIPSYPL----------CIYLINQKWF----------- 363

  Fly   377 IGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFM--ESPTGVLVLFCLY--ILLPGLSISIMI 437
                         |||..|.|.|.:..|:.:::.|:  :..|||..:...:  .||..|:||...
Human   364 -------------GRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAF 415

  Fly   438 GAIV----DLVPTHLRSKAVSFCMSLGRLGIIAA 467
            ..:.    :|.||.:|:..:..|....|:|.|.|
Human   416 NIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIA 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	116/475 (24%)
		MFS	34..>189	CDD:119392	40/162 (25%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	107/420 (25%)
		MFS_1	111..450	CDD:284993	107/420 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840