Protein Alignment CG31103 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 116/559 - (20%)
• Similarity: 191/559 - (34%)
• Gaps: 210/559 - (37%)

  Fly    15 WDYD----MVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAA 75
            |||:    :....||    ||.|:...|    ..|..:|.:.|:..||..
Human   185 WDYNGLPVLTTNAIG----QWDLVCDLG----WQVILEQILFILGFASGY--------------- 226

  Fly    76 SVTGIFLSTYIWGYISDDIGRRRVLL----------YGNFASN------ALQFVLMFVTSVWLFN 124
                :||     ||.:|..|||.::|          .|..|:.      ||:|:|.|
Human   227 ----LFL-----GYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGF-------- 274

  Fly   125 IINLLVGISVGAVSAALYAYLSEFNIPRHR-AVAINYSTMFVSVTAIYVPATAWLVLSSNWAITM 188
               ||.|:.:|     :|....|...|..| .||:....:.|.
Human   275 ---LLAGVDLG-----VYLMRLELCDPTQRLRVALAGELVGVG---------------------- 309

  Fly   189 GDFVF-------RPWRLLLLVSLLPGFIGGLILLY-----YPESPKFLLSQEKNNEAIEAVAWIS 241
            |.|:|       :.||.|..:...|..   |.|.|     :.||.::|:.:.:..||...:..::
Human   310 GHFLFLGLALVSKDWRFLQRMITAPCI---LFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILA 371

  Fly   242 KFNRGKSIQQVLSCDEFTLKSEDPVGENLLGE--SQGCGILSKICRATIPL-------FHKPHGF 297
            :.||                   |.|: :|||  .:....|...|    ||       |.....:
Human   372 ERNR-------------------PHGQ-MLGEEAQEALQDLENTC----PLPATSSFSFASLLNY 412

  Fly   298 NFILCNLALFGMF-FSSNGMQLWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPIS 361
            ..|..||.:.|.. |.::.::..:..:   ..|...:...:|.:|:      :.|..|.|
Human   413 RNIWKNLLILGFTNFIAHAIRHCYQPV---GGGGSPSDFYLCSLLA------SGTAALAC----- 463

  Fly   362 SKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSG----VLLHFMES-----PT- 416
                        .||      |:.::..||:.:||.::   ||:|    |||...:.     ||
Human   464 ------------VFL------GVTVDRFGRRGILLLSM---TLTGIASLVLLGLWDCEHPIFPTV 507

  Fly   417 -------------GVLVLFCLYILLPGLSISIMIGAI-VDLVPTHLRSKAVSFCMSLGRLGIIA- 466
                         ..:..|.:..|....:.:|:...: .:::||.:|.:.:...|:||.||.::
Human   508 WAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSG 572

  Fly   467 -ATNL---MGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501
             |..|   .|..||     ...:..|.|: ||:.:..||
Human   573 PAQRLHMGHGAFLQ-----HVVLAACALL-CILSIMLLP 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	103/513 (20%)
		MFS	34..>189	CDD:119392	33/171 (19%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930