Protein Alignment CG31103 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 108/529 - (20%)
• Similarity: 195/529 - (36%)
• Gaps: 164/529 - (31%)

  Fly    30 QWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETT-----------QAEKGVMMAASVTGIFLS 83
            ||.||.::|.:..||.|..:......:..|..|.:|           |:.|.|:....:||:.:.
Human    95 QWQLLHLNGTIHSTSEADTEPCVDGWVYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVG 159

  Fly    84 TYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYLSEF 148
            ..|.|::||..|||.:|.:.............|..:..::.::..|.|.|
Human   160 GIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFS--------------- 209

  Fly   149 NIPRHRAVAINYSTMFVSVTAIYVPATAWL--------VLSSNWAITMGD-------FVFRPWRL 198
                        |.:.:|..::  |.|.|:        |:.|:.|:::|.       :|||.|:.
Human   210 ------------SMIIISNNSL--PITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQT 260

  Fly   199 LLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCD--EFTLK 261
            |.:|:.:|.|:..|:..:..||.::|:...|.:|.::|:..:::.|..|:.::.|:.:  ..|::
Human   261 LHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQ 325

  Fly   262 SEDPVGENLLGESQGCGIL------SKIC-------RATIPLFHKPHGFNFILCNLALFGMFFSS 313
            .|....:.   ::..|.:.      .:||       ..|||.:........:..|:.|..:.:.:
Human   326 EELDAAQT---KTTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQHVGSNIFLLQVLYGA 387

  Fly   314 NGMQLWFPEIVNRSSGAENNSSTVC-EILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLI 377
            ..:      ||.            | .:|::......:::.|                  |.||:
Human   388 VAL------IVR------------CLALLTLNHMGRRISQIL------------------FMFLV 416

  Fly   378 GFSIQGLILNP--LGRKNVLLAALAV----ATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIM 436
            |.||......|  :....|.||.|.:    ||.|.|.:||:|
Human   417 GLSILANTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIE----------------------- 458

  Fly   437 IGAIVDLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTL---------IV 492
                  |:||.||::|....::..|:|...|..||          |..:|..||         |:
Human   459 ------LIPTVLRARASGIDLTASRIGAALAPLLM----------TLTVFFTTLPWIIYGIFPII 507

  Fly   493 CIVIVHYLP 501
            ..:||..||
Human   508 GGLIVFLLP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	99/492 (20%)
		MFS	34..>189	CDD:119392	33/173 (19%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	108/529 (20%)
		MFS	143..516	CDD:119392	94/479 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840