Protein Alignment CG31103 and SLC22A25

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_955384.3
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 547
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 97/513 - (18%)
• Similarity: 182/513 - (35%)
• Gaps: 132/513 - (25%)

  Fly    30 QWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAAS-----------VTGIFLS 83
            ||.|:.::|....||....:......:..|..|.:|...|..::..|           :.|:.:.
Human    95 QWKLIHLNGTFPNTSEPDTEPCVDGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVG 159

  Fly    84 TYIWGYISDDIGRRRVLLYGNFASNALQFVLM-----FVTSVWLFNIINLLVGISVGAVSAALYA 143
            ..::|::||..||:.||.:     :.||..::     |..::.::..:..|.|.:..::......
Human   160 GNLYGHLSDRFGRKFVLRW-----SYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVL 219

  Fly   144 YLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGD--FVFRPWRLLLLVSLLP 206
            .:.|:...:..|:|:                |..|..:|...||:|.  ||.|...:|.||...|
Human   220 LIVEWITHQFCAMAL----------------TLTLCAASIGHITLGSLAFVIRDQCILQLVMSAP 268

  Fly   207 GFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCD--EFTLKSEDPVGEN 269
            .|:..|...:..||.::|:...|..|.::.:...:..|..|:.:.:|:.:  :.|:|.|....:.
Human   269 CFVFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQK 333

  Fly   270 LLGESQGCGIL------SKIC-------RATIPLF----HKPHGFNFILCNLALFGMFFSSNGMQ 317
               :...|.:|      .:||       .:|||.:    |..|..|.:.....|||.
Human   334 ---KHSLCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGA-------- 387

  Fly   318 LWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQ 382
                                            ||...:|..|.:
Human   388 --------------------------------VTLLANCVAPWA--------------------- 399

  Fly   383 GLILNPLGRK--NVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGAIVDLVP 445
               ||.:.|:  .:||..|....|..::....|..|..:||..|.:....|.|:.......:|:|
Human   400 ---LNHMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIP 461

  Fly   446 THLRSKAVSFCMSLGRLGIIAATNLM--GVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501
            :.:|.:|.....:...:|...|:.:|  .:..:|.....:.:|.   |:..::|..||
Human   462 SIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFA---ILSGLVVLLLP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	66/330 (20%)
SLC22A25	NP_955384.3	MFS_OAT	109..516	CDD:340932	90/497 (18%)