DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31103 and CG3690

DIOPT Version :9

Sequence 1:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	130/541 - (24%)
Similarity:	245/541 - (45%)	Gaps:	66/541 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DYDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGI 80
            |::..::..|:|....:||:.:....:.:|.....||.|:.:::|:.:.:..:||::.|.:..|:
  Fly    31 DFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAGM 95

  Fly    81 FLSTYIWGYISDDIGRRRVLLYGNFASNAL----------QFVLMFVTSVWLFNIINLLVGISVG 135
            ..|..:|||::|..|||.:|:.| :|::.:          :..||         :...|.|..:.
  Fly    96 ISSAVLWGYLADIKGRRNLLIVG-YAADTICVLGGALSQSRIQLM---------VFKYLGGFCMS 150

  Fly   136 AVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLL 200
            ...|.|..||:|.:..:||...:....:..|:..:.:|..|.|:|...|.|.:.......|:..:
  Fly   151 GPFAVLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFV 215

  Fly   201 LVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEA-------------------------VAWI 240
            .|:.||..:..::..::|||||||:|:.:|.||::|                         :..:
  Fly   216 AVTALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPV 280

  Fly   241 SKFNRGKSIQQVLSCDEFTLKSEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLA 305
            .|..:.::|...|......::.:||..::....|...|...     ..|||.||:....:...|.
  Fly   281 KKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQ-----LRPLFTKPYLGLSLWVYLL 340

  Fly   306 LFGMFFSSNGMQLWFPEIV-------NRSSGAENNSSTVCEILSVPVEQPN-----VTE---TLD 355
            .|.:....|.|:||.|::.       |..|| |:.|:::|.||...|.:..     ||.   |::
  Fly   341 NFCVLLGQNTMRLWLPQLFASINEYENLMSG-ESQSTSICNILEYSVNRTQSQLEAVTRNDPTVE 404

  Fly   356 CTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLV 420
            |...|:..||.:||:|..|..:.:.:.|.::|.:|.|.::.:.|.:|....:.:::..|....:.
  Fly   405 CHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVA 469

  Fly   421 LFCLYILLPGLSISIMIGAIVDLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAM 485
            |..|::.:..:|.:.:|.|.|.|.||.||:..||..|..||||.:........::...|...|.|
  Fly   470 LASLFVTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPPFLM 534

  Fly   486 FTCTLIVCIVIVHYLPIRNSA 506
            .:..::....:..:||::|.|
  Fly   535 ISAFMLAGCFMAAFLPLKNKA 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	120/495 (24%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	39/164 (24%)
CG3690	NP_001284764.1	SP	42..549	CDD:273317	124/522 (24%)
		MFS	49..>195	CDD:119392	36/155 (23%)
		MFS	419..>550	CDD:119392	30/130 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458189
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1117
	7	7.000