DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31103 and Slc22a5

DIOPT Version :9

Sequence 1:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_062142.1	Gene:	Slc22a5 / 29726	RGDID:	3702	Length:	557	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	94/412 - (22%)
Similarity:	170/412 - (41%)	Gaps:	96/412 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 GIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYA 143
            |:.:.::|.|.:||..||:.||...........|:.:|..:..:|.::.:|||  :|.:|..:.|
  Rat   152 GVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVG--MGQISNYVAA 214

  Fly   144 YLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLVSLLPGF 208
            ::....| ..:::.|.::|:.|.:  .|  |..::||      .:..:..|.||:|||...:||.
  Rat   215 FVLGTEI-LSKSIRIIFATLGVCI--FY--AFGFMVL------PLFAYFIRDWRMLLLALTVPGV 268

  Fly   209 IGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEF-TLKSEDPVGENL-- 270
            :.|.:..:.||||::|:||.:..||...:...:|||...:...:....|. .|.|:.|...::
  Rat   269 LCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSELQDLNSKKPQSHHIYD 333

  Fly   271 LGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEI-----VNRSSGA 330
            |..::...|:      ||        .:.||......|.|    |:.|..|.:     ||
  Rat   334 LVRTRNIRII------TI--------MSIILWLTISVGYF----GLSLDTPNLHGDIYVN----- 375

  Fly   331 ENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVL 395
                   |.:|:. ||.|                         |:::.:    |:|..|.|:..:
  Rat   376 -------CFLLAA-VEVP-------------------------AYVLAW----LLLQHLPRRYSI 403

  Fly   396 LAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSI----SIMIGAIVDLVPTHLRSKAVSFC 456
            .|||.:.  ..|||.....|:.:..|....:::....|    |::.....:|.||.:|:..|
  Rat   404 SAALFLG--GSVLLFIQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGV--- 463

  Fly   457 MSLGRLGIIAATNLMGVMLQPY 478
                  |:.:..:.:|.:|.||
  Rat   464 ------GVSSTASRLGSILSPY 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	91/407 (22%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	26/109 (24%)
Slc22a5	NP_062142.1	2A0119	12..520	CDD:273328	94/412 (23%)
		MFS	123..510	CDD:119392	94/412 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	537..557
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840