Protein Alignment CG31103 and Slc22a2

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_113772.1
• Gene: Slc22a2 / 29503
• RGDID: 61936
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 451
• Identity: 105/451 - (23%)
• Similarity: 180/451 - (39%)
• Gaps: 122/451 - (27%)

  Fly    79 GIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTS--VWLFNIINLLVGISVGAVSAAL 141
            |.|:...:.||::|..||:..||. ....||:...||.::.  .|:. :...|.|:...|.....
  Rat   159 GFFIGAMMIGYLADRFGRKFCLLV-TILINAISGALMAISPNYAWML-VFRFLQGLVSKAGWLIG 221

  Fly   142 YAYLSEF-NIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLVSLL 205
            |..::|| .:...|.|.|.|...|          |..|::.:..|     :|...||.|.....|
  Rat   222 YILITEFVGLGYRRMVGICYQIAF----------TVGLLILAGVA-----YVIPNWRWLQFAVTL 271

  Fly   206 PGFIGGLILLYY---PESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQ---QVLSCDEFTLKSED 264
            |.|   ..|||:   ||||::|:||.|..:|::.:..|:|.| |||:.   |.|:.||...|...
  Rat   272 PNF---CFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKN-GKSVPVSLQNLTPDEDAGKKLK 332

  Fly   265 PVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEIVNRSSG 329
            |...:|:...|       |.:.|:.|.:.                         ||
  Rat   333 PSILDLVRTPQ-------IRKHTLILMYN-------------------------WF--------- 356

  Fly   330 AENNSSTVCE--ILSVPVEQPNVTETLDCTDPISSKTYID---NLVVGF--AFLIGFSIQGLILN 387
               .||.:.:  |:.:.:...|:              |:|   :.:|.|  ||:|     .|.::
  Rat   357 ---TSSVLYQGLIMHMGLAGDNI--------------YLDFFYSALVEFPAAFII-----ILTID 399

  Fly   388 PLGRK------NVLLAALAVATLSGVL----LHFMESPTGVLVLFCLYILLPGLSISIMIGAIV- 441
            .:||:      |::..|   |.|:.|.    |.:::     :.:.||..:  |::::..:..:|
  Rat   400 RVGRRYPWAVSNMVAGA---ACLASVFIPDDLQWLK-----ITIACLGRM--GITMAYEMVCLVN 454

  Fly   442 -DLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501
             :|.||::|:..|..|.|:..:|.|....|:..:...:......:|....:|...:|..||
  Rat   455 AELYPTYIRNLGVLVCSSMCDIGGIITPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	66/253 (26%)
Slc22a2	NP_113772.1	2A0119	12..525	CDD:273328	105/451 (23%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O15244	284..288		3/3 (100%)