DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31103 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	533	Identity:	95/533 - (17%)
Similarity:	178/533 - (33%)	Gaps:	160/533 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LESNTLGPNV--------WDYD-------MVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSII 54
            ||.||....|        |.||       :|:|        |.|:
  Rat    93 LEPNTSSHGVATEGCKDGWVYDRSIFPSTIVME--------WDLV-------------------- 129

  Fly    55 VIASQCEFETTQAEKGVMMAASVTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTS 119
                 ||..|.   :.:..:..::|:.:...::|.::|.:||:..|::..........|..:|.|
  Rat   130 -----CEARTL---RDLAQSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGS 186

  Fly   120 VWLFNIINLLVGISVGAVSAALYAYLSEFNIPRHRAVA---INYSTMFVSVTAIYVPATAWLVLS 181
            ...:.|...|:|::...:.....:.:.|:...|.|.||   :.:|   .::..:.:...|:|:
  Rat   187 FSAYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFS---FTLGQLILAGVAYLI-- 246

  Fly   182 SNWAITMGDFVFRPWRLLLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRG 246
                        ||||.|......|..:..|...:.|||.::||...|..:|::.:..::..|..
  Rat   247 ------------RPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGR 299

  Fly   247 KSIQQVLSCDEFTLKSEDPVGENLLGESQGCGILSKIC-----RATIPLFHKPHGFNFILCNLAL 306
            |:                 .||.|..|.....|.::..     .:.:.||..| |...:.|.|
  Rat   300 KA-----------------EGERLTIEVVSSYIQNEFASVRTSNSILDLFRTP-GIRKVTCCL-- 344

  Fly   307 FGMFFSSNGMQLWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVV 371
                     |.:||            ::|.....|::.:::            .....|:...:.
  Rat   345 ---------MMVWF------------SNSVAYYGLAMDLQK------------FGLSIYLVQALF 376

  Fly   372 GFAFLIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVL--------------VLF 422
            |...:....:....:..:||:..:.:.|.:|.|..:...|:......|              ...
  Rat   377 GIIDIPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQTLRTVQAALGKGCLASSFI 441

  Fly   423 CLYILLPGLSISIMIGAIVDLVPTHLRSKAVSFCMSLGRLGIIAA---TNL--MGVMLQPYCNTT 482
            |:| |..|           :|.||.:|...:.|.....|||.:||   |.|  :..:|.|.....
  Rat   442 CVY-LFTG-----------ELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVLPPVSFGA 494

  Fly   483 FAMFTCTLIVCIV 495
            .::.....::|.:
  Rat   495 TSVLAGMAVICFL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	82/472 (17%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	23/157 (15%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	90/523 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840