Protein Alignment CG31103 and Slc22a3

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 510
• Identity: 109/510 - (21%)
• Similarity: 177/510 - (34%)
• Gaps: 138/510 - (27%)

  Fly     2 HSSLESNTLGPNVWDYDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQ 66
            ||::.|        .:|:|.      ...|:|.|...:|.:
Mouse   132 HSTIVS--------QFDLVC------SNAWMLDLTQAILNL------------------------ 158

  Fly    67 AEKGVMMAASVTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVG 131
                        |.....:..||.:|..||..:.|...|.......|:.|..:..:|.|...|.|
Mouse   159 ------------GFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQG 211

  Fly   132 ISVGAVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRP- 195
            :.........:..::|....:.|.:......||.::..|.:|..|:               |.|
Mouse   212 VFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAY---------------FTPS 261

  Fly   196 WRLLLLVSLLPGFIGGLILLYY---PESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDE 257
            |:.:.|...||.|   |.||||   ||||::|:::::..:|::.:..::|.| ||.:....|  |
Mouse   262 WQGIQLAISLPSF---LFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCN-GKHLSSNYS--E 320

  Fly   258 FTLKSEDPVGENLLGESQGCGILSKICRATI--PLFHKPHGFNFILCNLALFGMFFSSNGMQLWF 320
            .|:..|:              :.:..|...:  |...|        |.|.|         |..||
Mouse   321 ITVTDEE--------------VSNPSCLDLVRTPQMRK--------CTLIL---------MFAWF 354

  Fly   321 PEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLI 385
                        .|:.|.:.|.:.:            ..|....|||..:.|...|.|..:..|.
Mouse   355 ------------TSAVVYQGLVMRL------------GLIGGNLYIDFFISGLVELPGALLILLT 395

  Fly   386 LNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGAIV----DLVPT 446
            :..|||:....|:..||.:|.::..|:  |.|:..|......|..|.|::....:.    :|.||
Mouse   396 IERLGRRLPFAASNIVAGVSCLVTAFL--PEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPT 458

  Fly   447 HLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501
            .||:..||.|..|...|.|.|..|:..:...:......:|.....||..:|..||
Mouse   459 TLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	62/312 (20%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	109/510 (21%)
		Proline-rich sequence. /evidence=ECO:0000250|UniProtKB:O75751	284..288		3/3 (100%)