Protein Alignment CG31103 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 103/487 - (21%)
• Similarity: 188/487 - (38%)
• Gaps: 107/487 - (21%)

  Fly    16 DYDMVLEKI-GYGKTQWVLLLVSGLLTITSVAA------------QQAMSIIVIASQ----CEFE 63
            |.|:..||. .:.:.||.||.::|  |.:||..            .|:..:..|.::    ||
  Rat    80 DSDLRPEKCRRFVQPQWDLLHLNG--TFSSVTEPDTEPCVDGWVYDQSTFLSTIITEWDLVCE-- 140

  Fly    64 TTQAEKGVMMAASVTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINL 128
             :|:...:.....:|||.:...::|.::|..|||.:|:..:......:....|..:..::..:..
  Rat   141 -SQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCAAFAPTFLIYCSLRF 204

  Fly   129 LVGISVGAVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVF 193
            |.|||...|.......:.|:..|:.:|:|   :.:.:...||.....|.|.           |..
  Rat   205 LAGISFSTVLTNSALLIIEWTRPKFQALA---TGLLLCAGAIGQTVLAGLA-----------FTV 255

  Fly   194 RPWRLLLLVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEF 258
            |.|..|.|...:|.|...:...:..||.::|:...|..:.::.:..::..|..|:...||:.:..
  Rat   256 RNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVV 320

  Fly   259 -TLKSEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPE 322
             |:..|:      |..||....|..:.|.  |...|    ...|.:|..|.::.|..|:
  Rat   321 RTIMKEE------LEASQTKSSLWDLFRT--PNLRK----RICLLSLVRFVVWLSVIGL------ 367

  Fly   323 IVNRSSGAENNSSTVC--EILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLI 385
            ::|......|.....|  .|:::|                             |.|:|.    .:
  Rat   368 LINFQHLRINVFLLQCLLGIITIP-----------------------------ANLVGI----FL 399

  Fly   386 LNPLGRKNVLLAALAVATLSGV-LLHFMESPTGVLVLFCLYILLPG----LSISIMIGAIVDLVP 445
            :|.|||:   ::.|.:.:|.|: :|..:..|..:.:|..:.....|    :|:|..:....:|:|
  Rat   400 VNHLGRR---ISQLFIISLFGISILAIIFVPQEMQILRMVLATFGGVFSFVSVSSALVHANELLP 461

  Fly   446 THLRSKAVSFCMSLGRLGIIAATNLMGVMLQP 477
            |.:|:.|      ||.:||..:|   |..|.|
  Rat   462 TIIRATA------LGVIGIAGST---GAALSP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	68/324 (21%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	91/456 (20%)