Protein Alignment CG31103 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 106/454 - (23%)
• Similarity: 157/454 - (34%)
• Gaps: 122/454 - (26%)

  Fly    79 GIFLSTYIWGYISDDIGRRR------VLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAV 137
            |..|...|.|...|..|||.      ||..|..||.||  ...|.|.:    ::.||.|.::...
Human    29 GWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEAL--AASFPTLL----VLRLLHGGTLAGA 87

  Fly   138 SAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLV 202
            ..|||....|...|.||......:.:|..|..:.:|..|.||              :.||||
Human    88 LLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALV--------------QDWRLL--- 135

  Fly   203 SLLPGFIGGLILLY------YPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLK 261
            ..|...:.||:||:      :||||.:||:..:...| ..:.|                 .|...
Human   136 QGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARA-RKILW-----------------RFAEA 182

  Fly   262 SEDPVGENLLGESQGCGILSKI-CRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEIVN 325
            |....|::.|.|:.....|:.: .|:..|.:|.|.|.        |.......||:.|.|..:|.
Human   183 SGVGPGDSSLEENSLATELTMLSARSPQPRYHSPLGL--------LRTRVTWRNGLILGFSSLVG 239

  Fly   326 RSSGAENNSSTVCEI--------LSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQ 382
            ....|....|...::        |...:|                       .....||:
Human   240 GGIRASFRRSLAPQVPTFYLPYFLEAGLE-----------------------AAALVFLL----- 276

  Fly   383 GLILNPLGRKNVLLAALAVATLSGVLL----HFMESPTGVLVLFCLYILLPGLSISIMIGAI--- 440
             |..:..||:.|||....|..|:.:||    .::   .|..||| |.:|  ||..|..:.|:
Human   277 -LTADCCGRRPVLLLGTMVTGLASLLLLAGAQYL---PGWTVLF-LSVL--GLLASRAVSALSSL 334

  Fly   441 --VDLVPTHLRSKAVSFCMSLGRLGIIAAT-----NLMGVMLQPYCNTTFAMFTCTLIVCIVIV 497
              .::.||.:|...:...:..|.||..|..     ...|..||   ...||......::|::::
Human   335 FAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQ---QVVFASLAVLALLCVLLL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	synapt_SV2	<17..>324	CDD:130366	66/257 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	104/440 (24%)