DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31103 and str-176

DIOPT Version :9

Sequence 1:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_001294210.1	Gene:	str-176 / 13197055	WormBaseID:	WBGene00006220	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	581	Identity:	127/581 - (21%)
Similarity:	213/581 - (36%)	Gaps:	156/581 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSLESNTL-----------GPNV--WDYDMVLE--KIG----YGKTQWVLLLVSGLLTITSVAAQ 48
            ||||..||           .|.|  ...:|::|  |:|    :...:|..:||..:..:|:..|.
Worm    11 SSLEQETLLKPEDVEAVVQTPIVPKKSLEMMVEEKKVGSLDDFITLRWYCMLVLLMAELTAFTAT 75

  Fly    49 QAMSIIVIA---------------------------SQCE------FETTQAE--------KGVM 72
            .:..::|.|                           :.||      |::.|.|        |.|.
Worm    76 ASSKVMVFAGANPAVIGCGGTPLNGCHELAAFRNETNLCEPDLRYQFKSVQVEFNYICEDAKKVK 140

  Fly    73 MAASVT--GIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVG 135
            ...:|.  |:.:...|:|.:||..|||:.||.....:....::..:...::.|.:...|.|:..|
Worm   141 NTITVQTFGVLVGAAIFGQVSDTFGRRKALLISTLGNGLFNWITAYSPDLFYFMVWRTLAGVFTG 205

  Fly   136 AVSAALYAYLSEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLL 200
            .|:.....::.| ||||...:.|..|..: |...|..|..||  |..:|         |...:::
Worm   206 GVTVVQMVFMVE-NIPRKDRMWIQNSITW-SPNLILFPFVAW--LCQDW---------RTMSVVI 257

  Fly   201 LVSLLPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSEDP 265
            ..|.:..|:..|||   .|||::|:.:.:..||.:::..|.|.::       |..:.|    |..
Worm   258 AASSIATFLACLIL---EESPRWLIQKGRIEEARKSLIRIRKTDK-------LYDETF----EKQ 308

  Fly   266 VGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFSSNGMQLWFPEIVNRSSGA 330
            :.|.|..|::.....||..        |.:.|..:.|...:.       ...|.|
Worm   309 LDEVLHVEAEKHARSSKKA--------KKYTFIHLFCTWKMI-------AQSLTF---------- 348

  Fly   331 ENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVG---FAFLIGFSIQGLILNPLGRK 392
              .:...|....|.....|:       :.:|...|.:..::|   :...|..||....|...|||
Worm   349 --ITGITCTTFIVYSLMYNM-------EKLSGSLYWNLAIMGASRWIINIAVSIADYKLPWFGRK 404

  Fly   393 NVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGAIV---------------D 442
            .:...|: :.||..:|          ::...||....|..|:|...|.|               :
Worm   405 MINQIAM-ICTLFALL----------MIAVYLYFGYNGQLIAIGTVAAVSMCSQLFIAKYMMVNE 458

  Fly   443 LVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCN-TTFA-MFTCTLIVCIVIVHYLP 501
            |.||.:|:.|||...::.|:|.:.:..|.  .|..|.. ..:| :|:|.|...||:..:||
Worm   459 LYPTAVRNLAVSAVSTMSRIGSMFSPQLF--YLSDYAEWIPYAVLFSCQLYDFIVLSLFLP 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	105/506 (21%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	43/197 (22%)
str-176	NP_001294210.1	2A0119	13..527	CDD:273328	125/579 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162885
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840