DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cad96Ca and Pdgfrl

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_081116.3	Gene:	Pdgfrl / 68797	MGIID:	1916047	Length:	375	Species:	Mus musculus

Alignment Length:	206	Identity:	44/206 - (21%)
Similarity:	72/206 - (34%)	Gaps:	63/206 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 VRGEQSGEEEQPDEEVTPTTPVRISSTTPKSRTKLTPITANNSTRVESAIPAETTTPSGGHHNNS 302
            |.|:.|.:.::|.|:    ...||..|..|::.|:..:...:||        ::|.
Mouse    19 VGGQHSPKNKRPKEQ----GENRIKPTNKKAKPKIPKVKDRDST--------DSTA--------- 62

  Fly   303 SSPITIFSLKSGTIPIVVTVGGFFVAIAVLLAYLCRRRL---CAISRT-------LKKTKEKEEL 357
                     ||.:|.:.....|.|...|..::.|..:.|   |..|:.       |...|:....
Mouse    63 ---------KSQSIMMQAMGNGRFQRPAATVSLLAGQTLELRCKGSKVEWSYPAYLDTFKDSRLT 118

  Fly   358 AKKSNQ----SQLSSTLTDDSRNSMVMQQWQGPVAFANRYVPWERDQQMGIATSQLSTGVTNGGV 418
            .|:|.:    :.::||..|....|.    |:   ...|.|: ..||        :..||.|....
Mouse   119 VKQSERYGQLTLVNSTAADTGEFSC----WE---QLCNGYI-CRRD--------EAKTGSTYIFF 167

  Fly   419 SSPG---VPSP 426
            :..|   ||||
Mouse   168 TEKGELFVPSP 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568
		PTKc	474..742	CDD:270623
Pdgfrl	NP_081116.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..63		12/72 (17%)
		Ig	80..143	CDD:299845	12/62 (19%)
		IG_like	83..>143	CDD:214653	11/59 (19%)
		I-set	272..373	CDD:254352
		Ig	293..372	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900