Protein Alignment Cad96Ca and PTK6

DIOPT Version :10

• Sequence 1: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_005966.1
• Gene: PTK6 / 5753
• HGNCID: 9617
• Length: 451
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 105/298 - (35%)
• Similarity: 150/298 - (50%)
• Gaps: 41/298 - (13%)

  Fly   461 DRWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGI----TTVAVKTLKESATEVDRKDLL-- 519
            |.||.||........||.|.||:|:          ||:    ..||:|.       :.|.:||
Human   182 DDWERPREEFTLCRKLGSGYFGEVF----------EGLWKDRVQVAIKV-------ISRDNLLHQ 229

  Fly   520 ----SELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSN 580
                ||::.||.|. |.:::.|....:..||.::|.|.:.:|.|...||.|           ...
Human   230 QMLQSEIQAMKKLR-HKHILALYAVVSVGDPVYIITELMAKGSLLELLRDS-----------DEK 282

  Fly   581 VLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKS 645
            ||...:|....:|||:||.||.|:..|||||||||||:.::..|||.|||.|| :|...:| ...
Human   283 VLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLAR-LIKEDVY-LSH 345

  Fly   646 EGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPE 710
            :..:|.:|.|.|:|....:|.|||:||||||:.|:.:.|..||||:|..:...:|..|||:..|.
Human   346 DHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPL 410

  Fly   711 HCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHTE 748
            .|...::.:|..||..||::||.|..:.:.|......|
Human   411 ECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSYE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		PTKc	474..742	CDD:270623	98/277 (35%)
PTK6	NP_005966.1	SH3_Brk	12..69	CDD:212781
		SH2_PTK6_Brk	75..174	CDD:198221
		Linker	171..190		5/7 (71%)
		PTKc_Srm_Brk	184..444	CDD:133248	103/290 (36%)