Protein Alignment Cad96Ca and csf1rb

DIOPT Version :10

• Sequence 1: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: XP_009293978.1
• Gene: csf1rb / 568405
• ZFINID: ZDB-GENE-091118-1
• Length: 961
• Species: Danio rerio
• Alignment Length: 992
• Identity: 247/992 - (24%)
• Similarity: 370/992 - (37%)
• Gaps: 332/992 - (33%)

  Fly    10 SRIIHCRKQL-TSWRRRSLL---------LTIIVVTATVVSLISQEAEAHNQNAPPI-LYVR--E 61
            |.::||..|. ..|:.|..:         |.:...||...........:|......| |||:  :
Zfish    43 SFVLHCDGQAEIIWKTRRRIHQKNLSQNELVVQKATAEHTGTYRCSYRSHTDIYSEIHLYVKDPD 107

  Fly    62 RNWRISETE----KVGQ--IIDRVRAEDPDGDDLIFGIEPRFSLPGGENDASPPEKIPFQIDRET 120
            :.:..|:|.    |.|.  ::|.: ..:|.|.:        |||......|.||
Zfish   108 KAFTTSQTRVIVIKEGSSFLLDCL-LTNPAGTE--------FSLQMTNGSAVPP----------- 152

  Fly   121 GVVTLNESLAGRAGQNFLIYITVTDGSYTAKNEVFINILGERENSSGYRPQTSISNVVHNISQFL 185
               .:|.:...|.|    |.|.....|||......:|:.|.:..|..::     ..|:....:
Zfish   153 ---GMNYTADPRRG----ILIPNLQPSYTGDYVCMVNMSGVQWKSKVFQ-----ITVIKKAQE-- 203

  Fly   186 PRFDQLPGVQSIR---NGLPNSRPGGWYPPVPQNNIFGPPPFGNNY-------PPPPPNIPGVRG 240
            |....||.:|.:|   ..|.       .|...||:        |:|       |....|.
Zfish   204 PPSVSLPALQYVRIVGESLQ-------IPCYIQNH--------NHYYNFTWSSPKKVLNF----- 248

  Fly   241 EQSGEEEQPDEEVTPTTPV----------------------RISST-----TPKSRTKLTPITAN 278
            |:..::::..|:|..|..:                      |.|||     ..|...:||||.::
Zfish   249 EREIKKKKKCEQVCATIYLTFQQLKMSDTENLTCTAMNEAGRNSSTAVLRVVEKPYLELTPILSS 313

  Fly   279 ----NSTRVE-------------SAIP----AETTTPSGGH---------HN------------- 300
                |.|.|.             .|.|    |:..|||..|         |:
Zfish   314 EYKGNETNVVRMHGDQLELGVHIQAYPDVEWAKWKTPSSNHSYEETFHKIHDSDIYMATIRLKNV 378

  Fly   301 -----------------NSS---------SPITIFSLKSGTIPIVVTVGGFFVAIAVLLAYLCRR 339
                             |:|         .|.|:...::|.:....|  |:.:.......|...|
Zfish   379 GAQDYGDYIFSAGSTSVNASIIFTVHVYQKPTTVIKWENGVVSCAAT--GYPIPSIQWFQYEVNR 441

  Fly   340 RLCAISRT-----------LKKTKEKEELAKKSNQSQL------------SSTLTDDSRNSMVMQ 381
            .||:.:||           .:::.|.|.:..||...::            ::|..||.  .....
Zfish   442 ALCSDNRTSGVELMANQSISEQSGEYEPVLVKSALPEITANADLIFECVATNTAGDDC--DFYTF 504

  Fly   382 QWQGPVAFANRYVPWERDQQMGIATSQLSTGV-TNGGVSSPGVPSPGT----------------- 428
            .:.||                 ..||..||.| .:.|:|  |..|..|
Zfish   505 TFSGP-----------------RPTSVWSTSVLISLGLS--GALSVATLWMLILLYKNRKAQKYE 550

  Fly   429 -------GEPGSN---LGPGCLTGGAGSSGAPENAFAGEANCDRWEFPRYRLKFFNILGEGAFGQ 483
                   ...|:|   :.|         |..|.|        .:.||||.:||...:||.||||:
Zfish   551 IQWKIIEVNDGNNYTFIDP---------SQLPYN--------KKLEFPRNKLKLGQVLGAGAFGK 598

  Fly   484 VWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTF 548
            |.:..|..:..:|.||.||||.||.||...:|:.|:|||:::..:.||.|:|:|||.||...|..
Zfish   599 VVQATAIGLVKDETITRVAVKMLKPSARFEEREALMSELKILNYIGPHENIVNLLGACTQGGPML 663

  Fly   549 VILEYVNRGKLQTYLRSSRAERHYGNTHG------KSNV-------------------------- 581
            :|.||...|.|..:|| .|.|.......|      .||:
Zfish   664 MITEYCCHGDLLNFLR-QRVETFVNTVLGVQSFAEDSNLYKNVTIQKQHPARNAYSGLDSFRDTP 727

  Fly   582 ----------------------LTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTC 624
                                  |.:.||..|.||||:|||:|.|:..|||||||||:|:.|....
Zfish   728 SGQMPKEPFQESCNEELENMLSLDNMDLLMFSYQVAQGMDFLASKNCIHRDLAARNVLVADCRIV 792

  Fly   625 KVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYP 689
            |:.|||.|||::....|..|...:||::||:.||:::.:::|:||:||:|:|:|||.:||.:|||
Zfish   793 KICDFGLARDIMNDTNYVVKGNARLPVKWMSPESIFECLYTVQSDVWSYGVLLWEIFSLGMSPYP 857

  Fly   690 GISA-ADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL------HT 747
            .::. |...:.::|||.:.:|:....|:|.||..||..:|..||.||:|.:::.|||      ..
Zfish   858 NVAIDAQFYKMIKDGYHMPQPDFAPHEMYTIMKMCWRQEPTTRPTFADITELIAKLLPMQTSEDN 922

  Fly   748 EMDYIELERFPDHNYYN 764
            |..|.||.|....|:.|
Zfish   923 ETMYPELRRHLMANHCN 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637	23/104 (22%)
		PTKc	474..742	CDD:270623	117/322 (36%)
csf1rb	XP_009293978.1	Ig_3	22..87	CDD:464046	9/43 (21%)
		IG_like	116..197	CDD:214653	22/112 (20%)
		IG_like	210..299	CDD:214653	19/108 (18%)
		Ig	327..405	CDD:472250	10/77 (13%)
		Ig strand B	330..334	CDD:409353	0/3 (0%)
		Ig strand C	344..348	CDD:409353	1/3 (33%)
		Ig strand E	371..375	CDD:409353	0/3 (0%)
		Ig strand F	385..390	CDD:409353	0/4 (0%)
		Ig strand G	398..401	CDD:409353	1/2 (50%)
		Ig	411..>467	CDD:472250	10/57 (18%)
		Ig strand B	418..422	CDD:409256	1/3 (33%)
		Ig strand C	431..435	CDD:409256	0/3 (0%)
		Ig strand E	452..456	CDD:409256	0/3 (0%)
		Protein Kinases, catalytic domain	548..914	CDD:473864	130/383 (34%)