Protein Alignment Cad96Ca and fgfr1b

DIOPT Version :9

• Sequence 1: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_001155204.1
• Gene: fgfr1b / 567905
• ZFINID: ZDB-GENE-060503-14
• Length: 740
• Species: Danio rerio
• Alignment Length: 842
• Identity: 237/842 - (28%)
• Similarity: 371/842 - (44%)
• Gaps: 239/842 - (28%)

  Fly    17 KQLTSWRRRSLLLTIIVVT--ATVVSLISQEAEAHNQNAPPILYVRERNWRISETEKVGQIIDRV 79
            :.|.|||   ||:.::::|  .||            |:.|.:            ||: |.|:  .
Zfish    11 RMLKSWR---LLVLLLILTQLCTV------------QSRPAV------------TEQ-GHIV--A 45

  Fly    80 RAEDPDGDDL------------IFGIEPRFSLPGG------------------ENDASPPEKI-- 112
            .:||.|.|:.            :..:.||::.|..                  :.:.:|..|:
Zfish    46 SSEDEDDDESSSEENKPSSSQELLPMAPRWAQPEKMEKKLHAVPASKTVKFRCQAEGNPIPKLRW 110

  Fly   113 -----PFQIDRETGVVTLNESLAGRAGQNFLIYITVT---DGSYTAKNEVFINILGERENSSGYR 169
                 .|:.|:..|...|.|.:.      .:|..:|.   .|:||..          .||..|..
Zfish   111 LKNGKEFKRDQRIGGYKLREHMW------TIIMESVVPSDKGNYTCL----------VENEYGSI 159

  Fly   170 PQTSISNVVHNISQFLPRFDQLPGVQSIRNGLPNSRPGGWYPPVPQNNIFGPPPFGNN------- 227
            ..|...:||          ::.|....:..|||.:|..               ..|::
Zfish   160 NHTYQLDVV----------ERSPHRPILYAGLPANRTA---------------VVGSDVEFVCKV 199

  Fly   228 YPPPPPNIP-----GVRGEQSGEEEQPDEEVTPTTPVRISSTTPKSRTKLTPITANNSTRVESAI 287
            :..|.|:|.     .|.|.|.|.:..|...|..|..:   :||.|.    ..:....:...|.|
Zfish   200 FSDPQPHIQWLKHIRVNGSQLGPDGLPYVRVLKTAGL---NTTDKE----MEVLQLRNVSFEDA- 256

  Fly   288 PAETTTPSG-----GHHNNSSSPITIFSLKSGTIP-----------IVVTVGGFFVAIAVLLAYL 336
             .|.|..:|     .||   |:.:|:  :|:.|.|           ::..:|.|.:.:.|.:|
Zfish   257 -GEYTCLAGNSIGISHH---SAWLTV--VKAPTAPSAVPSQSYLEVLIYCIGFFLIFLMVGIA-- 313

  Fly   337 CRRRLCAISRTLKKTKEKEELAKKSN-QSQLSSTLTDDSRNSMVMQQWQGPVAFANRYVPWERDQ 400
                      |:.|.:..   :|||: .|||:                   |....:.:|..|..
Zfish   314 ----------TIVKIRSS---SKKSDFNSQLA-------------------VHKLAKSIPLRRQI 346

  Fly   401 QMGI-ATSQLSTG---VTNGGVSSPGVPSPGTGEPGSNLGPGCLTGGAGSSGAPENAFAGEANCD 461
            .:.: ::|.|::|   |....:||.|.|               :..|......|::.      |
Zfish   347 TVSVESSSSLNSGVMLVRPSRLSSSGTP---------------MLSGVSEYELPQDP------C- 389

  Fly   462 RWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNE--GITTVAVKTLKESATEVDRKDLLSELEV 524
             ||..|.||.....||||.||||...||..::.::  .||.||||.||..|||.|..||:||:|:
Zfish   390 -WEVSRERLVLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEM 453

  Fly   525 MKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKS---------- 579
            ||.:..|.|:::|||.||...|.:||:|:.::|.|:.|||:.|       .||..
Zfish   454 MKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARR-------PHGMEYCYNPDPLPI 511

  Fly   580 NVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERK 644
            ..::..||.|..||||:||:||.|:..|||||||||:|:|:|:..|:||||.||||.....|::.
Zfish   512 ESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKT 576

  Fly   645 SEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKP 709
            :.|:||::|||.|:|:|.|::.:||:||||:|:|||.|||.:||||:...::.:.:|:|:|::||
Zfish   577 TNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLREGHRMDKP 641

  Fly   710 EHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLH--TEMDYIELERFPDHNYYNIVSLS 769
            ..|.:|||.:|..||...|.:||.|.::::.||:.|.  :..:|:||. .|....|:.|.|:
Zfish   642 SACTQELYLMMKDCWHAVPTQRPTFKQLVEDLDRTLSLISNQEYLELS-VPLEPMYSQVILN 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637	23/138 (17%)
		STYKc	470..741	CDD:214568	126/282 (45%)
		PTKc	474..742	CDD:270623	125/279 (45%)
fgfr1b	NP_001155204.1	I-set	80..167	CDD:254352	16/102 (16%)
		Ig2_FGFR	83..167	CDD:143265	16/99 (16%)
		IG_like	182..278	CDD:214653	24/122 (20%)
		Ig3_FGFR-2	190..278	CDD:143266	22/99 (22%)
		PKc_like	383..684	CDD:304357	135/315 (43%)
		Pkinase_Tyr	397..673	CDD:285015	126/282 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.770