DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cad96Ca and si:ch211-167j9.5

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	XP_693602.5	Gene:	si:ch211-167j9.5 / 565221	ZFINID:	ZDB-GENE-131121-210	Length:	400	Species:	Danio rerio

Alignment Length:	459	Identity:	116/459 - (25%)
Similarity:	201/459 - (43%)	Gaps:	101/459 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 IVVTVGGFFVAIAVLLAYLCRRRLCAISRTLKKTKEKEELAKKSNQSQLSSTLTDDSRNSMVMQQ 382
            |:::|.|..|....:|.:||..:..::.:|::..|:..........|..||   ..|.|.:.:.:
Zfish    11 ILISVYGVTVFFMAVLGFLCFHKYRSLKKTIRDLKQGRPTVIPRAASHDSS---PPSPNVLTLPE 72

  Fly   383 WQGPVAFANRYVPWERDQQMGIATSQLSTGVTNGGVSSPGVPSPGTGEPGSNLGPGCLTGGAGSS 447
            ...|:|.:    |.:|.|             |......|...|.
Zfish    73 APEPIAES----PLQRQQ-------------TKSSCKFPWKTSQ--------------------- 99

  Fly   448 GAPENAFAGEANCDRWEFPRYRLKFFNIL------GEGAFGQVWRCEATNINGN-EGITTVAVKT 505
                            :.||:..:..|::      .||.|     .:|..|.|. .|.:.:..|.
Zfish   100 ----------------QVPRFTKEDLNLIQLIKAGREGVF-----YKARIIRGTCRGHSLITCKI 143

  Fly   506 LKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAE- 569
            .||..|.   |.:..|..:|:.|..|.||:.||...|.::|..:|:|:::.|.|:|:::..:.|
Zfish   144 GKEGMTS---KQMEHEASIMRKLAYHKNVMQLLDWNTAEEPYLLIMEFMSYGTLRTFVQKHKDEL 205

  Fly   570 -------RHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILI-TDDHTCKV 626
                   ||:               |...|.:|.||::|.|:.::|.|||.||||: ......||
Zfish   206 SADPELQRHF---------------TIASYHIAMGMEHLRSKMVVHCDLALRNILVGRFPWETKV 255

  Fly   627 ADFGFARDV--ITSKIYERKSEGK--LPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTP 687
            |:||.|||:  :.|:...||.:.|  :|:||...|....|.:|.|.|:|::||::||:...|:.|
Zfish   256 AEFGLARDLTRMRSRRSSRKKQHKERVPLRWYPPEYFRSNYYSFKGDVWAYGIVLWEMQMFGTLP 320

  Fly   688 YPGISAA-DVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHTEMDY 751
            |..:|.: :|:..:..|.:...|..||.|:..|:..|||.....||.|.:|:::|:.::.::.||
Zfish   321 YSNLSTSEEVVYNICAGLKNPIPRTCRPEMEQIIRDCWSDPYTSRPSFTDIVKILENIVESDGDY 385

  Fly   752 IELE 755
            :.::
Zfish   386 VHID 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	89/291 (31%)
		PTKc	474..742	CDD:270623	89/288 (31%)
si:ch211-167j9.5	XP_693602.5	TyrKc	109..375	CDD:197581	89/288 (31%)
si:ch211-167j9.5	XP_693602.5	PKc_like	118..376	CDD:304357	88/280 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910