DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cad96Ca and si:ch73-206d17.1

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	XP_689652.2	Gene:	si:ch73-206d17.1 / 561155	ZFINID:	ZDB-GENE-090313-143	Length:	393	Species:	Danio rerio

Alignment Length:	435	Identity:	116/435 - (26%)
Similarity:	203/435 - (46%)	Gaps:	81/435 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 SLKSGTIPIVVTVGGFFVAIAVLLAYLCRRRLCAISRTLKKTKEKEELAKKSNQSQLSSTLTDDS 374
            ::.||:.|.....|...:|:.::.:.|....|..:|:.:.....|...|:|         :|..|
Zfish     8 NISSGSDPACYDEGSGPLAVIIIPSLLALSTLIVVSQIIWSFVTKRSSAQK---------ITSSS 63

  Fly   375 RNSMVMQQWQGPVAFANRYVPWERDQQMGIATSQLSTGVTNGGVSSPGVPSPGTGEPGSNLGPGC 439
            .|             .|     ||:.      .||..|:             |:..|.:.|||
Zfish    64 SN-------------VN-----EREH------VQLDAGI-------------GSLRPANVLGP-- 89

  Fly   440 LTGGAGSSGAPENAFAGEANCDRWEFP-RYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAV 503
                                   .|.| :..|:...:|..|.:|.:...:....|.:   |.|.:
Zfish    90 -----------------------LELPVQCTLEGVEVLQMGRYGPICMGQLKQDNTS---TAVMI 128

  Fly   504 KTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRA 568
            ||||:.:|:.:..:.:..:....::..|.|:|.||.|.|.:.|.:::||....|.|..:|.|.|.
Zfish   129 KTLKDRSTQSESAEFMDLVLFHAAVSKHENIVKLLFCQTRRTPMYLLLEASVPGNLLNFLWSLRE 193

  Fly   569 ERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTS-RGIIHRDLAARNILITDDHTCKVADFGFA 632
            :|     .|:|:|.:...:.....|:|.|:|||.| ..:||.|:||||:||....:.||:...||
Zfish   194 DR-----CGESSVFSEKSVFLVAKQIAAGLDYLHSHHRVIHGDVAARNMLIGSAFSVKVSGLDFA 253

  Fly   633 RDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVM 697
            .:....|..:|:.|..:|::|.|.|.:.....:.:||:||||||::|::||||.|||.:..::|:
Zfish   254 FESRQKKKVDREQEANVPVKWQAPERMMRLPLTDRSDVWSFGILLYEMITLGSPPYPDLDPSEVL 318

  Fly   698 RKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLD 742
            .:....||:::||:|...|::::.||...:.::||:::.||::||
Zfish   319 PRTLAHYRMKRPENCGAPLFDLIKYCCMWNFKDRPVYSAIIRLLD 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	87/271 (32%)
		PTKc	474..742	CDD:270623	86/268 (32%)
si:ch73-206d17.1	XP_689652.2	PKc_like	102..363	CDD:304357	86/268 (32%)
si:ch73-206d17.1	XP_689652.2	Pkinase_Tyr	102..362	CDD:285015	86/267 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810