Protein Alignment Cad96Ca and Tie

DIOPT Version :9

• Sequence 1: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 175/628 - (27%)
• Similarity: 276/628 - (43%)
• Gaps: 153/628 - (24%)

  Fly   253 VTPTTPVRISSTTPKS-----RTKLT---------PITANNSTRVESAIPAETTTPSGG------ 297
            |||.|..:.|.||..|     .|.||         |.:.:.:|...:..|...|.||..
  Fly   632 VTPRTQTQPSHTTDSSPKILRTTVLTSIRSTVHPRPTSTSTTTSTTTTAPPAVTAPSNEVYIGIV 696

  Fly   298 HHNNSSSPITIFS------------LKSGTIPIVVTVGGFFVAIAVLLAYLCRRRLCAISRTLKK 350
            ..::|:||..|.|            ::...:..:|.|....:.:|.::.||.|.  ..|.|..|:
  Fly   697 ESSSSASPADISSTVIANERDLNMEMRRMNLVTLVLVAVGVIPLAAIILYLVRN--FVIRRRAKQ 759

  Fly   351 TK-------EKEELA--KKSNQSQLSSTLTDDSRNSMVMQQWQGPVAFANRYVPWERDQQMGIAT 406
            ::       :::.::  ||.:    |....||..:.:..|..|......|............:..
  Fly   760 SEVFDVCITDQQPISPVKKVD----SKYQVDDDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPM 820

  Fly   407 SQLSTGVTNGGVSSPGVPSPGTGEPGSNLGPGCLTGGAGSSGAPENAFAGEANCDRWEFPRYRLK 471
            ||.|....|            ....|:|              ..:.:.|.|.:    :|.|..::
  Fly   821 SQASQRDAN------------HNRYGNN--------------DDKTSLASEFH----DFERSNIR 855

  Fly   472 FFNILGEGAFGQVWRCEATNINGNEGIT-TVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVV 535
            ..::||||.|||||:.||.:::|:.|.| .|||||::..:.:|..||   |..:|:.|..|.|||
  Fly   856 LKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLKD---EANIMRKLGSHQNVV 917

  Fly   536 HLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHY--GNTHGKSNV--LTSCDLTSFMYQVAK 596
            .|||.|.:.:|..:|:||..||:|.:.||::|:..:.  .:..|..::  |:...|..|...:|.
  Fly   918 TLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAGFALDIAC 982

  Fly   597 GMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIY-------------------- 641
            ||:|:..|.|:||||||||:|:..:..||:.|||.:.|:...::.
  Fly   983 GMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAHKFK 1047

  Fly   642 --------------------------------ERKSE------GK---LPIRWMATESLYDNIFS 665
                                            |:||.      ||   |||||||.|||..::|:
  Fly  1048 FDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYHMFT 1112

  Fly   666 VKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQE 730
            .::|||:|||::|||.|||||||..::..:|:|:|..|.|.:.|:..|.|.||:|..||..:|..
  Fly  1113 TETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHM 1177

  Fly   731 RPLFA----EIIQMLDKLLHTE---MDYIELERFPDHNYYNIV 766
            ||.||    ||.:.|.|.:..:   .||:::..|.:...:.:|
  Fly  1178 RPSFAQSRLEITRSLHKWVDDDSAASDYMDVSGFSEDLEHGVV 1220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	120/340 (35%)
		PTKc	474..742	CDD:270623	120/337 (36%)
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	117/331 (35%)
		PTKc	860..1187	CDD:270623	118/329 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930