Protein Alignment Cad96Ca and FER

DIOPT Version :10

• Sequence 1: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: XP_011541571.1
• Gene: FER / 2241
• HGNCID: 3655
• Length: 837
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 98/279 - (35%)
• Similarity: 149/279 - (53%)
• Gaps: 37/279 - (13%)

  Fly   475 ILGEGAFGQVWRCEATNINGN-EGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLL 538
            :||:|.||:|::       |. :..|:|||||.||...:..:...|.|.:::|..: |.|:|.|:
Human   568 LLGKGNFGEVYK-------GTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYD-HPNIVKLI 624

  Fly   539 GCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTS 603
            |.||.:.|.::|:|.|:.|...|:||..:.|            |....|..|....|.||.||.|
Human   625 GVCTQRQPVYIIMELVSGGDFLTFLRRKKDE------------LKLKQLVKFSLDAAAGMLYLES 677

  Fly   604 RGIIHR---------------DLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRW 653
            :..|||               ||||||.|:.:::..|::|||.:|.. ...:|......::||:|
Human   678 KNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKISDFGMSRQE-DGGVYSSSGLKQIPIKW 741

  Fly   654 MATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYN 718
            .|.|:|....:|.:||:||||||:||..:||..||||::......:|..|||:..|:||..::..
Human   742 TAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISK 806

  Fly   719 IMYYCWSHDPQERPLFAEI 737
            ||..||.:.|:.||.|:|:
Human   807 IMMKCWDYKPENRPKFSEL 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		PTKc	474..742	CDD:270623	98/279 (35%)
FER	XP_011541571.1	F-BAR_Fer	5..238	CDD:153370
		SMC_prok_B	107..>393	CDD:274008
		SH2_Fps_family	453..538	CDD:198224
		Protein Kinases, catalytic domain	566..831	CDD:473864	98/279 (35%)