DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cad96Ca and ver-4

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_509835.2	Gene:	ver-4 / 186632	WormBaseID:	WBGene00006897	Length:	1216	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	112/337 - (33%)
Similarity:	171/337 - (50%)	Gaps:	44/337 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   463 WEFPRYRLKFFNILGEGAFGQV---WRCEATNIN-GNEGITTVAVKTLKESATEVDRKDLLSELE 523
            :|.....|:....||.|.||.|   :...|::.| |.|...:||:|:..:|:....:|....||:
Worm   863 YEIDLENLEILETLGSGQFGIVKKGYLNMASSKNFGFESRLSVAIKSSTDSSNMELQKMFFEELK 927

  Fly   524 VMKSLEPHINVVHLLGCCT---DKDPTFVILEYVNRGKLQTYLRSSR-------AERHY-GNTHG 577
            :|.::..|.||:.|:|..|   :....|::.|.::.|.|:.:||..|       .|:.| ..|:.
Worm   928 LMCAIPKHPNVLSLVGAVTKNMEIGELFIVTELIDGGNLREFLRERRDVFANELVEKGYIFLTNV 992

  Fly   578 KSNV-----------------LTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCK 625
            :.||                 |.:.||.|...|:|.|||:|.:...:|||||.||:||:.....:
Worm   993 RENVPKREVEKEQLLIDEFNSLCTSDLLSIGLQIANGMDWLANIPCVHRDLACRNVLISKTKIIR 1057

  Fly   626 VADFGFARDVITSKIYERKSEG---KLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTP 687
            :||||.|:. .|.|.|.|..|.   .||:|||..||:.|..|:.|||:||:||.::||.|||.||
Worm  1058 IADFGLAKK-HTDKAYYRVRESLDTPLPVRWMPLESITDLTFTQKSDVWSYGICLYEIFTLGGTP 1121

  Fly   688 YPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML--------DKL 744
            ||......::..::.|...::|.:|.:::|.||..||...|.:||.|||.|::.        .||
Worm  1122 YPDCPNFSLVEYIKTGNINKRPSNCHKDVYKIMKMCWQASPDDRPTFAECIKLFKNHIQYFASKL 1186

  Fly   745 LHTEMDYIELER 756
            |......:|.|:
Worm  1187 LQQIEKDLECEK 1198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	106/305 (35%)
		PTKc	474..742	CDD:270623	105/310 (34%)
ver-4	NP_509835.2	ig	609..679	CDD:278476
		IG_like	611..692	CDD:214653
		IG_like	709..782	CDD:214653
		IGc2	714..772	CDD:197706
		STYKc	870..1175	CDD:214568	106/305 (35%)
		PTKc	874..1176	CDD:270623	105/302 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810