DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cad96Ca and Pdgfra

DIOPT Version :9

Sequence 1:NP_651349.1 Gene:Cad96Ca / 43026 FlyBaseID:FBgn0022800 Length:773 Species:Drosophila melanogaster
Sequence 2:NP_001076785.1 Gene:Pdgfra / 18595 MGIID:97530 Length:1089 Species:Mus musculus


Alignment Length:413 Identity:134/413 - (32%)
Similarity:200/413 - (48%) Gaps:102/413 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   462 RWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMK 526
            ||||||..|....|||.||||:|....|..::.::.:..||||.||.:|...:::.|:|||::|.
Mouse   585 RWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMT 649

  Fly   527 SLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR------------------------ 567
            .|.||:|:|:|||.||...|.::|.||...|.|..||..:|                        
Mouse   650 HLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFMSQHPEKPKKDLDIFGLNPAD 714

  Fly   568 -AERHY--------GN------------------------------------------------- 574
             :.|.|        |:                                                 
Mouse   715 ESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVK 779

  Fly   575 ---THGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVI 636
               :...|..||..||.||.||||:||::|.|:..:||||||||:|:......|:.|||.|||::
Mouse   780 NLLSDDDSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIM 844

  Fly   637 TSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISA-ADVMRKV 700
            ....|..|....||::|||.||::||:::..||:||:|||:|||.:||.|||||:.. :....|:
Mouse   845 HDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKI 909

  Fly   701 RDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL---------HTEMDYIELE- 755
            :.|||:.||:|...|:|.||..||:.:|::||.|..:.::::.||         ...:|:::.: 
Mouse   910 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDH 974

  Fly   756 ------RFPDHNYYNIVSLSGEK 772
                  |....|.|..|:...|:
Mouse   975 PAVARMRVDSDNAYIGVTYKNEE 997

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cad96CaNP_651349.1 Cadherin_repeat 65..164 CDD:206637
STYKc 470..741 CDD:214568 120/356 (34%)
PTKc 474..742 CDD:270623 119/353 (34%)
PdgfraNP_001076785.1 Ig_3 28..100 CDD:372822
Ig_PDGFR-alphabeta 228..311 CDD:143269
Ig4_PDGFR 313..413 CDD:143267
Ig_TrkABC_d4 416..497 CDD:143173
PTKc_PDGFR_alpha 555..956 CDD:173653 128/370 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1018..1089
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24416
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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