DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cad96Ca and kin-30

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_506771.3	Gene:	kin-30 / 180032	WormBaseID:	WBGene00002211	Length:	458	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	99/320 - (30%)
Similarity:	164/320 - (51%)	Gaps:	28/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   477 GEGAFGQVWRCEATNINGNEGITT---VAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLL 538
            |:|.||:|.:.....||...|...   ||||...:|..:...|.:|.|:::|.::..|.||:.::
Worm   140 GQGNFGKVNKALLKLINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIV 204

  Fly   539 GCCT------DKDPTFVILEYVNRGKLQTYLRSSRAERH--------YGNTHGKSNV---LTSCD 586
            |..|      .::...|:.|:|..|.|::.|:.:....|        .|.....|::   |::.|
Worm   205 GAITKQEKVIGREHNLVVTEFVEGGDLRSVLKYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSD 269

  Fly   587 LTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYER---KSEGK 648
            |.||.||:|.||:||.::..:|||||.||:.:..:...::.|||.||. .:.|.|.|   ..:..
Worm   270 LYSFAYQIANGMEYLAAKPCVHRDLALRNVFVKRNKMIRIGDFGLARH-HSKKSYYRMQCNPDTP 333

  Fly   649 LPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGI---SAADVMRKVRDGYRLEKPE 710
            |||.|:|.|...::.|:..:|:||:|:.::|:.:||.:||..:   .:.||:..::.||||..|.
Worm   334 LPIFWLAPECFNESKFTEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHYLKKGYRLSAPR 398

  Fly   711 HCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL-HTEMDYIELERFPDHNYYNIVSLS 769
            :|..|:|..|.|||:.|...||.|.|.......|: ..::..||.....:....|.:||:
Worm   399 YCNAEIYEFMLYCWNIDATLRPKFTECKDFCKSLITRKKLKKIESRLQMEEQLQNELSLA 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	93/289 (32%)
		PTKc	474..742	CDD:270623	93/290 (32%)
kin-30	NP_506771.3	TyrKc	134..428	CDD:197581	93/288 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910