DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cad96Ca and W03A5.1

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_498153.3	Gene:	W03A5.1 / 175744	WormBaseID:	WBGene00020966	Length:	803	Species:	Caenorhabditis elegans

Alignment Length:	295	Identity:	87/295 - (29%)
Similarity:	147/295 - (49%)	Gaps:	32/295 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   476 LGEGAFGQVWRCEATNINGNEGITTVAVKT--LKESATEVDRKDLLSELEVMKSLEPHINVVHLL 538
            :|:||||.|.:.:..|..|..  ..||||.  |:||:.: :|....||:|::: :..|.|:|...
Worm   500 IGKGAFGTVKKGKFRNSLGES--VPVAVKKLGLRESSKD-ERNPAFSEMEILE-MVAHPNIVFYY 560

  Fly   539 G--CCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYL 601
            |  ...|:...:::.|.::. .|..::..|.|            :|:..:....:.|:.:||.:|
Worm   561 GFSISGDEQALYLLFELMDT-SLDKFIDKSDA------------ILSENERLDILAQICRGMSFL 612

  Fly   602 TSR--GIIHRDLAARNILI------TDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATES 658
            .:|  .|:|.||||||:|:      ...:.||:.|.|.|:..:...........|:|.:|:..|.
Worm   613 HTRTPSIVHGDLAARNVLLKKHPVYIKKYICKITDLGLAKTCLDELYTSYDDPTKIPFKWLPPEV 677

  Fly   659 LYDNIFSVKSDIWSFGILMWEIVTLGSTPYPG-ISAADVMRKVRDGYRLEKPEHCRRELYNIMYY 722
            |.....|:|:|||:|||:.:|:......||.. :..:::.:.:.|||..||..|....:|||...
Worm   678 LGSRTLSLKTDIWAFGIVCFEVCDKVGEPYGACVPTSNLCQYLTDGYVHEKGLHMSDTIYNIALD 742

  Fly   723 CWSHDPQERPLFAEII-QMLDKLLHTE-MDYIELE 755
            |....|.|||.|||:: |.||.|:..: .|.::|:
Worm   743 CMRQHPIERPSFAELVDQFLDHLIENDGEDVLKLK 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	82/278 (29%)
		PTKc	474..742	CDD:270623	82/279 (29%)
W03A5.1	NP_498153.3	PTKc	498..761	CDD:270623	81/277 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910