DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cad96Ca and ver-1

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_497162.2	Gene:	ver-1 / 175182	WormBaseID:	WBGene00006894	Length:	1083	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	94/301 - (31%)
Similarity:	160/301 - (53%)	Gaps:	38/301 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   463 WEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGI-----TTVAVKTLKESATEVDRKDLLSEL 522
            :||.:..|:....:|.|.||.|.|          ||     |.||||:....::...:|.::.||
Worm   796 FEFHKDSLEILEPIGSGHFGVVRR----------GILKGTKTVVAVKSSSYRSSIGFQKVIVEEL 850

  Fly   523 EVMKSLEPHINVVHLLGCCTDK---DPTFVILEYVNRGKLQTYLRSSR---AERHYGN------- 574
            ::|.::..|.||:.|:|..|..   ...::::||::.|.|:.:|:..|   .:..:.|
Worm   851 KLMSAIPKHPNVLALVGAITKNLRHGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNFDENIPL 915

  Fly   575 THGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSK 639
            .....|.|::.||....:|:|.||::|.:...:|.:|..|.:||:...|.::.|:|...
Worm   916 IRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVGD------ 974

  Fly   640 IYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGY 704
             .:|||..   :||||.|::...:||.|||:|||||.::||.|||.||||.....::::.:::|.
Worm   975 -RQRKSSS---MRWMAPEAIEHQMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGS 1035

  Fly   705 RLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL 745
            |..:||:|...||::|..||...||:||.|:...::::|.|
Worm  1036 RNLQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELIEKQL 1076

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	90/288 (31%)
		PTKc	474..742	CDD:270623	89/285 (31%)
ver-1	NP_497162.2	Ig	<294..331	CDD:299845
		ig	576..652	CDD:278476
		IG_like	578..654	CDD:214653
		IG_like	660..731	CDD:214653
		IGc2	674..722	CDD:197706
		Pkinase_Tyr	803..1072	CDD:285015	90/288 (31%)
		PTKc	807..1073	CDD:270623	89/285 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910