DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cad96Ca and B0252.1

DIOPT Version :9

Sequence 1:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_495419.2	Gene:	B0252.1 / 174133	WormBaseID:	WBGene00015087	Length:	809	Species:	Caenorhabditis elegans

Alignment Length:	307	Identity:	88/307 - (28%)
Similarity:	139/307 - (45%)	Gaps:	36/307 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   475 ILGEGAFGQVWRCEATNINGN----EGITTVAVKTLKESAT---------EVDRKDLLSELEVMK 526
            :||||....|:   ...:.|.    :.|..|.:|..::.|.         |.:...|..|:..|:
Worm   514 LLGEGTISNVY---LGKLKGKSPIMQWIDRVEMKQYQDCAVAVRVPSHFDEPEEDQLQREIASMR 575

  Fly   527 SLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNV--LTSCDLTS 589
            .|..|.::..|||.....|....:||..:...:: ||...|......|:.|.:.:  :....|..
Worm   576 QLRHHDHIALLLGWTNKNDLVCSLLELTHMNLIK-YLSQIRETAEQDNSSGFTPMSRIPFQVLYK 639

  Fly   590 FMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGK-LPIRW 653
            .:|::..|::|:.||.::||||.|||:|:|.....|::.|||..:....|........: ||:||
Worm   640 IIYEICDGIEYIHSRNLVHRDLTARNVLLTTGLRAKISGFGFCSEPDDPKFAANSLALRYLPVRW 704

  Fly   654 MATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPG-ISAADVMRKVRDGYRLEKPEHCRRELY 717
            :|.|..... ||||||.||||:||:|:.:||..||.. |...:::..:|.|.....|::|.::.|
Worm   705 LAPECFIGK-FSVKSDSWSFGVLMYEMFSLGEQPYEDLIRPEEIIESIRKGRVPAHPKYCSKQTY 768

  Fly   718 NIMYYCWSHDPQERPLFAEIIQMLDKLLHTEMDYIELERFPDHNYYN 764
            .||..|:......||.|.:    |....|.:          ..||||
Worm   769 KIMQSCYQSFMSRRPNFTQ----LKNAFHVQ----------STNYYN 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	82/282 (29%)
		PTKc	474..742	CDD:270623	82/283 (29%)
B0252.1	NP_495419.2	PKc_like	515..792	CDD:389743	83/285 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810