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Protein Alignment Bili and KRIT1

DIOPT Version :9

Sequence 1:	NP_001163722.1	Gene:	Bili / 43019	FlyBaseID:	FBgn0039282	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_001337601.1	Gene:	KRIT1 / 889	HGNCID:	1573	Length:	736	Species:	Homo sapiens

Alignment Length:	457	Identity:	108/457 - (23%)
Similarity:	173/457 - (37%)	Gaps:	103/457 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 LTNSSYMPQHHKCNNG---------NDAQSNPAIQKRLMATSSTSNFATAG-------------- 414
            |.:..:.|.|:.|..|         ...:.||.:....:  ||..:||..|
Human   317 LDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQL--SSPLHFAAGGGHAEIVQILLNHPE 379

  Fly   415 --------------------------KAASNLTRALQNVIPTC-VYLMSRVAVHMEIE-GTAQCP 451
                                      :||..|..|:....... :|.|......:|:: |.....
Human   380 TDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTV 444

  Fly   452 SQVMLAAALGCEELGISNKLLAQSVFGLWMTSALLEMQLKAHHCPYIVRVAWPNLLQKFSNSSPS 516
            .|:|....|..|         .|..|.:|:.|..|.:|||.:|.|......||.:|.:.:|..|
Human   445 QQIMEGMRLSQE---------TQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNLDP- 499

  Fly   517 DRKFDEPMIVLKRNVFFSKRDEEKIKDHRILELLYEEARNNVLTGRYIMEPVHSLMLGGIQARIE 581
              :.:.|.:.|:|:|......|::|:|...:.:|::|||.|:|.|.|.......:.|..:..:|.
Human   500 --QRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIV 562

  Fly   582 LGPYNSHTHTIGFF-RENQARFLPPHVAKSSTWLWLPISQKNSAEVKLLEQFKRVPQTATTRK-- 643
            .|.|.|..|..||. .||....:|....||....|..         ::|.::|.:..:....|
Human   563 YGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTN---------RILHEYKNLSTSEGVSKEM 618

  Fly   644 --LMRKYLEFCWALPFYGAAYFHGQI---EQPVRGIMALVNQKDMEVLVAVNERGVFVIDPYECT 703
              |.|.:|:.||.:|.||||:|.|||   ..|       .|.|.:.|.|.||.:|:.:::.....
Human   619 HHLQRMFLQNCWEIPTYGAAFFTGQIFTKASP-------SNHKVIPVYVGVNIKGLHLLNMETKA 676

  Fly   704 LLLGLRYEDLSWDYAKPSASDDPECLTCIFLQFDAVENGIQVSKLMQIFSKQAAMIDALISHFTD 768
            ||:.|:|....|......        ||  .|..::||.:.    ..:.:|||.::..|:.....
Human   677 LLISLKYGCFMWQLGDTD--------TC--FQIHSMENKMS----FIVHTKQAGLVVKLLMKLNG 727

  Fly   769 QI 770
            |:
Human   728 QL 729

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.