Protein Alignment Clbn and nemf

DIOPT Version :9

• Sequence 1: NP_001163721.1
• Gene: Clbn / 43018
• FlyBaseID: FBgn0259152
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: XP_002938173.3
• Gene: nemf / 100497173
• XenbaseID: XB-GENE-5772016
• Length: 1058
• Species: Xenopus tropicalis
• Alignment Length: 1106
• Identity: 496/1106 - (44%)
• Similarity: 680/1106 - (61%)
• Gaps: 173/1106 - (15%)

  Fly     1 MKTRFNTFDIICGVAEL-QKLVGWRVNQIYDVDNKTYLFRMQGTGAVEKVTLLIESGTRFHTTRF 64
            ||:||||.||...:||| ..|:|.||:.:|||||||||.|:|...:  |..||:|||.|.|||.|
 Frog     1 MKSRFNTIDIRAVIAELSDSLLGLRVHNVYDVDNKTYLIRLQKPDS--KAVLLVESGIRIHTTEF 63

  Fly    65 EWPKNMAPSGFSMKLRKHLKNKRLEKVQQMGSDRIVDFQFGTGDAAYHVILELYDRGNVILTDYE 129
            ||||||.||||:||.|||||::||..::|:|.|||||||||:.:||||:|:|||||||::|||:|
 Frog    64 EWPKNMMPSGFAMKCRKHLKSRRLVSIKQLGVDRIVDFQFGSDEAAYHLIVELYDRGNIVLTDHE 128

  Fly   130 LTTLYILRPHT-EGENLRFAMREKYPVERAKQPTKELELEALVKLLENARNGDYLRQILTPNLDC 193
            ...|.|||..| |.::::||:||.||::.||.|...|.:|.|.::||.|:.||.|:::|.|:|..
 Frog   129 YLILNILRFRTDEADDVKFAVREHYPIDHAKAPEPLLSVEKLKEILEKAQKGDQLKRVLNPHLPY 193

  Fly   194 GPAVIEHVLLSHGLDNHVIKKETTEETPEAEDKPEKGGKKQRKKQQNTKLEQKPFDMVNDLPILQ 258
            |..:|||.||..||.:                              |.|::|  .....||..:.
 Frog   194 GATLIEHCLLDTGLSS------------------------------NVKVDQ--ISGPEDLEKVH 226

  Fly   259 QAVKDAQELIAEGNSGKSKGYIIQVKEEKPT--ENGTVEFFFRNIEFHPYLFIQFKNFEKATFES 321
            .|::.|:|.:......|.||:|||.:|:||:  .:...|..|.|.||||:||.|..|......:|
 Frog   227 TALRKAEEYMDVTQHFKGKGFIIQKREKKPSLEPDKPSEDIFTNEEFHPFLFAQHCNNTYIELDS 291

  Fly   322 FMEAVDEFYSTQESQKIDMKTLQQEREALKKLSNVKNDHAKRLEELTKVQDVDRKKAELITSNQS 386
            |.:|||||:|..|.|:||:|.||||::|||||.||:.||.:|||.|...||.|:.|.|||..|..
 Frog   292 FNKAVDEFFSKMEGQRIDLKALQQEKQALKKLENVRKDHEERLESLQHAQDADKAKGELIEMNLD 356

  Fly   387 LVDNAIRAVQSAIASQLSWPDIHELVKEAQANGDAVASSIKQLKLETNHISLMLSDPY------- 444
            :||.||:.|:||:|:|:.|.:|..:|||||..||:||.:||:|||:||||:::|.:||
 Frog   357 IVDRAIQVVRSALANQIDWKEIGLIVKEAQIQGDSVALAIKELKLQTNHITMLLKNPYTLSEEGS 421

  Fly   445 DNDEDDDLKDP------------------EVTVVDVDLALSAWANARRYYDMKRSAAQKEKKTVD 491
            :::|::..::|                  :..:|||||:|||:|||::|||.||.||:|.:||::
 Frog   422 EDEEEEKEEEPKGKKKKSKNKQPKKVQKNKPVLVDVDLSLSAYANAKKYYDHKRHAAKKSQKTIE 486

  Fly   492 ASQKALKSAERKTQQTLKEVRTISNIVKARKVFWFEKFYWFISSENYLVIGGRDAQQNELIVKRY 556
            |::||.||||:||:||||||:|:|.|.|||||:|||||.|||||||||||.|||.||||||||||
 Frog   487 AAEKAFKSAEKKTKQTLKEVQTVSTIQKARKVYWFEKFLWFISSENYLVIAGRDQQQNELIVKRY 551

  Fly   557 MRPKDIYVHAEIQGASSVIIQNPTGEEIPPKTLLEAGSMAISYSVAWDAKVVTNSYWVTSDQVSK 621
            :.|.|:||||::.||:|.:|:|||||.:||:||.|||:||:.||.||||:|:|:::||..:||||
 Frog   552 LNPGDVYVHADLHGATSCVIKNPTGEPVPPRTLTEAGTMAVCYSAAWDARVITSAWWVHHNQVSK 616

  Fly   622 TAPTGEYLATGSFMIRGKKNFLPSCHLTMGLSLLFKLEDSFIERHLGERKVRSLEDDQ------- 679
            ||||||||.||||||||||||||..:|.||...|||:::..:.||.|||:|:.|::|.
 Frog   617 TAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFGFLFKVDEPCVWRHKGERRVKQLDEDMESVTSSN 681

  Fly   680 ----IDPNVKENEVEHDLLSDNED---------------------------ADSNINLSEPSSNT 713
                .:.|:..:..|.|..|..||                           ||.|.:  :.|||:
 Frog   682 TELAAEENIPLDAAEEDSNSSEEDEKLDTQEEQRGPCTDSMGLEQKEYMVPADQNSD--QESSNS 744

  Fly   714 EIT-----------AFPNTEVKIEH-DTGRIIVR---SDSVNPEIEETKES---------EVVLD 754
            |..           ::|:|.:.:.| .|.|.:.:   ::.|:..:|..|.|         :..|.
 Frog   745 EENSTIKEEAEKELSYPDTAIDLSHLQTKRTLSKAAPAELVDTPLENEKSSGRKHMSAKEKRELK 809

  Fly   755 KILKKTDDEETTIILAGPSRKKQVSAKKTKEDKARAKQEAAKQEVPPVSSEPKNPSQVKRGQKGK 819
            |..|..|.:|..     ||.:|:...||          :.|..:..|.:|....|  :|||||.|
 Frog   810 KKKKPNDKDEFQ-----PSEQKETDDKK----------DVADSQSAPQASTGNQP--MKRGQKSK 857

  Fly   820 LKKMKQKYKDQDDEEREIRMMILKSSG--KEKPQASADKVVEKSESTKEYVKPEKSAAPKNPV-- 880
            |||:|:||||||:|:|::.|.:|.|:|  ||.......|...|.|..|:..:..|...|: ||
 Frog   858 LKKIKEKYKDQDEEDRDLIMQLLGSAGSNKEDKGKKGKKGKMKEEPVKKPPQKAKGGGPR-PVKR 921

  Fly   881 ----------------------ELDDADEVPVGGD--VDVLNSLTGQPHEGDELLFAIPVVAPYQ 921
                                  :.::||:.|.|.:  .::|:|||||||..|.|||::||.|||.
 Frog   922 EGPADVFLTEDLHEMTLEEQQEDKEEADQDPQGTEEAENLLDSLTGQPHGEDVLLFSVPVCAPYT 986

  Fly   922 ALQNYKFKVKLTPGTGKRGKAAKLALNIFAKEKSCSAREKDLLKSIKEESLARNIPGKVKLSAPQ 986
            ::.|||:||||||||.|:|||||.|||.|...|..:.||||||:|:|:..|:||:|||||:|||.
 Frog   987 SMTNYKYKVKLTPGTHKKGKAAKTALNSFMHSKDSTVREKDLLRSVKDTDLSRNMPGKVKVSAPN 1051

  Fly   987 L 987
            |
 Frog  1052 L 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clbn	NP_001163721.1	YloA	1..643	CDD:224212	348/670 (52%)
		DUF814	531..630	CDD:283353	69/98 (70%)
		DUF3441	883..984	CDD:288752	59/102 (58%)
nemf	XP_002938173.3	YloA	1..638	CDD:224212	348/670 (52%)
		DUF3441	956..1048	CDD:403211	55/91 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	437	1.000	Domainoid score	I558
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3458
Inparanoid	1	1.050	845	1.000	Inparanoid score	I434
OMA	1	1.010	-	-		QHG54163
OrthoDB	1	1.010	-	-		D131285at2759
OrthoFinder	1	1.000	-	-		FOG0005262
OrthoInspector	1	1.000	-	-		oto103137
Panther	1	1.100	-	-	LDO	PTHR15239
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1916
SonicParanoid	1	1.000	-	-		X4285
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110