DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vig2 and zgc:103482

DIOPT Version :9

Sequence 1:	NP_733083.1	Gene:	vig2 / 43016	FlyBaseID:	FBgn0046214	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	XP_005161229.1	Gene:	zgc:103482 / 450001	ZFINID:	ZDB-GENE-041010-115	Length:	348	Species:	Danio rerio

Alignment Length:	446	Identity:	116/446 - (26%)
Similarity:	162/446 - (36%)	Gaps:	158/446 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NRYELLFMDDDD------SSGLAQPQIAAVVAAPKKPEPAK---APKAPKSKSEKENKPVVAARK 93
            ||:..|..|:.|      ::|..:.|      ..||.||.|   ..|:.|.:|:::.|.::.|
Zfish    19 NRFGQLLGDESDPFDILYAAGTEKKQ------KKKKEEPKKTSTTTKSVKKESQRDRKTILPA-- 75

  Fly    94 ANAPVAKNASPVKGGKGPAGGDVGRP-----KNPTANGANNQGRFNNNQRYGNKESNGEFGNELP 153
                         ||    ||.| ||     :.|.........:||:.::     ....|..|.|
Zfish    76 -------------GG----GGQV-RPGHEVVEEPIQRRVTFDRKFNDAEK-----PPLSFSVERP 117

  Fly   154 ----QRQFNNRDN------RGP--PRVRTG-EKFGKREFDRQSGSDRT-GVKSIDKREGGGAHNW 204
                .|....|..      |||  ||...| ::.|||||:|.|||||: .|:|.:||.|.|:.||
Zfish   118 VDVLDRPARGRGTGRGKGARGPGFPRSNDGFDQRGKREFERHSGSDRSRSVRSEEKRSGSGSRNW 182

  Fly   205 G------------SPKQDIEDLKTTGETSPQAEKEDSANEQSADPAVAAEEDESKQMTLDEWKAL 257
            |            ||.:::    |..|.:.:|.:.|..|..|....|.   :.:.:|||||||||
Zfish   183 GSVRDHMSVIEVASPSEEV----TENEETQEAVETDGENRPSETEEVI---EVAMEMTLDEWKAL 240

  Fly   258 RDQ-RAKPNYNLRKAGEGAADNAEWKKMIVLSKKKESNSEDELEYDPSLYPQRVGRLQRIVDIQF 321
            ::| |.|...|:||     .:::...|.:|:.|.|....:|.::.|...     .|....:..|.
Zfish   241 QEQSRPKVELNIRK-----TESSVPSKAVVIHKSKLLQKQDGMDEDVVF-----RRPANDITCQL 295

  Fly   322 NFNDGRKVGFRKGPRPGAGPREGGFRNDGPRGEGGYRNDGPRGEGGYRNDGPRGEGPRNEGPRGE 386
            .||      |....||..|                       |.||             .|.||.
Zfish   296 EFN------FGSLDRPTRG-----------------------GRGG-------------RGGRGR 318

  Fly   387 GYRNDGPRGEGFRGPRFNNGPSNGYENRQDNNRFGEKRRSAQKPLKVDDEAQFPTL 442
            |    ||.....|.|                    :|..||..|   ||...||.|
Zfish   319 G----GPSMPTLRSP--------------------QKFDSAPNP---DDPEDFPAL 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vig2	NP_733083.1	HABP4_PAI-RBP1	175..273	CDD:282609	44/111 (40%)
zgc:103482	XP_005161229.1	IHABP4_N	11..96	CDD:292792	25/102 (25%)
zgc:103482	XP_005161229.1	HABP4_PAI-RBP1	152..254	CDD:282609	42/108 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580733
Domainoid	1	1.000	97	1.000	Domainoid score	I7158
eggNOG	1	0.900	-	-		E1_KOG2945
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4255
OMA	1	1.010	-	-		QHG48663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002116
OrthoInspector	1	1.000	-	-		mtm6592
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12299
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1570
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.860