Protein Alignment TTLL5 and Ttll11

DIOPT Version :10

• Sequence 1: NP_733081.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_084050.1
• Gene: Ttll11 / 74410
• MGIID: 1921660
• Length: 727
• Species: Mus musculus
• Alignment Length: 853
• Identity: 199/853 - (23%)
• Similarity: 326/853 - (38%)
• Gaps: 207/853 - (24%)

  Fly    74 SPQKLAEEEPTSSEPSSKEALSGSTQQKIFLLKKPQQCDKS-----DKLTFSSPFKKILNRYSSS 133
            ||:|..|.|..:...::..|.:.:|:......:|.|..|..     ::|......|.:....:.:
Mouse     5 SPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPT 69

  Fly   134 DTSISSEGEEPANSSENKSRVLKTSQNAINIKLATDLSNESGYESIAPAKTISNTEVIEE---DQ 195
            ......|||         :||::....|  :.||...........:..|:..|.:.|...   ..
Mouse    70 RRHAPEEGE---------ARVVRRLPPA--LPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSM 123

  Fly   196 EETSEDDAECGINMPASKLKITYKFHQTETKLLRKLFNVHGLTEVQGENNNFNLLWTGVHMK-LD 259
            ...:.|.::...::.|.|:.:        .:|..|.|..       |.....::.|.||..: .|
Mouse   124 RPVTVDSSKARTSLDALKISL--------RQLRWKEFPF-------GRRLPCDIYWHGVSFRDSD 173

  Fly   260 IVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRDLV--VAHN 322
            |:..     :||.||...||.||..|.:.:..||:| ..:.::..|::::||.|.:..|  |...
Mouse   174 ILSG-----QVNKFPGMTEMVRKVTLSRALRIMQNL-FPEEYNFYPRSWILPEEFQLFVSQVQTV 232

  Fly   323 KHRGP-W----IVKPAASSRGRGIFIVNSP-----DQIPQDEQAVVSKYIVDPLCIDGHKCDLRV 377
            |...| |    ||||.:..:|.||:::..|     .....:..|||.:||..||.||..|.|:|:
Mouse   233 KEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRL 297

  Fly   378 YVLVTSFDPLIIYLYEEGIVRLATVKY-DRHADNLWNPCMHLCNYSINKYHSDYIRSSDAQDEDV 441
            |||:.|.|||.||:.::|:.|..|..| :.:..||.:..|||.|||:|.:...::.|..|   ..
Mouse   298 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSA---ST 359

  Fly   442 GHKWTLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLACAQSIISACRMFVPNGN---NCFELYGF 503
            |.|.|.|::|..|..:..|.:::..:|..|:||.|:|....:....:..:|.|.   .||::.||
Mouse   360 GSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGF 424

  Fly   504 DILIDNALKPWLLEINLSPSMGVD-----SP---------LDTKVKSCLMADLLTCVGIPAYSPE 554
            |||:...|||.|||:|.:|||.::     ||         :|.:||..::.|.|..:     .|.
Mouse   425 DILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLM-----DPL 484

  Fly   555 MKSHYDQKWSRFRSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRRGGF 619
            .|    :|...|......|....|..|.:....|.||::::         |:|:.:::.|
Mouse   485 KK----KKEIHFPDIYMDRKHRIPPVSDRMSSWKHKGSSLS---------IVRSQQMEKS----- 531

  Fly   620 VRIFPTDDSMQRYGNFLDSANGIPISTPNVQSQTFQTPIIQHNYNQMLHQNLYSKDGRQKQDDNN 684
               |.:.:.:.     .|...|
Mouse   532 ---FTSKEDLN-----CDPTGG------------------------------------------- 545

  Fly   685 EADRIWQYERALETDSEIPFVKKPTVEKCEVEGRRLRKIMLKKISNGSELTPFQARQTFSMYLES 749
                          |||      |..|      ..|..|.||::      .|..|:| |: ||..
Mouse   546 --------------DSE------PNPE------AHLPSICLKQV------FPKYAKQ-FN-YLRL 576

  Fly   750 VLRRLTEDPKDNHEKIILKFLNKFGGSVKPPVMFRN-MQTIKVASKARSAMVAKLLGDFLENYKR 813
            |         |....:.::||...|.....|..||. ::..|::|.:.|.....:|  :::..:|
Mouse   577 V---------DRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDIL--YIDITRR 630

  Fly   814 DTEAYVDSFDHFGMIPSSAYNQFL-----------MHAQESDLEAVLTLHTNVTGIMPFLYNRCG 867
            .....||..|. ||...:....|.           :|.|.:.|..:...|.:|......|.:| |
Mouse   631 WNSVTVDQRDS-GMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHR-G 693

  Fly   868 LSVPPTPP 875
            ..:...||
Mouse   694 RPLQRNPP 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL5	NP_733081.1	TTL	266..549	CDD:397308	104/312 (33%)
Ttll11	NP_084050.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..88		17/91 (19%)
		CPSase_L_D2	178..445	CDD:473076	95/270 (35%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q8NHH1	464..566		30/207 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..551		8/96 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	694..727		2/8 (25%)