Protein Alignment TTLL5 and Ttll4

DIOPT Version :10

• Sequence 1: NP_733081.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001414011.1
• Gene: Ttll4 / 690512
• RGDID: 1594742
• Length: 1198
• Species: Rattus norvegicus
• Alignment Length: 703
• Identity: 204/703 - (29%)
• Similarity: 336/703 - (47%)
• Gaps: 105/703 - (14%)

  Fly     2 PSSLCEALTNSSISFDYQKEDDWITSGKLGSREAVLVFRTNILNPKIRKTLSEKSSAQVLTDTKD 66
            ||..|.::.:..:               ||...|.:...:::....:.:..:..||..:....|:
  Rat   429 PSPTCGSVVDPQL---------------LGEDRAPVPPSSSLQPLGVAEVATRLSSVHLGQPGKE 478

  Fly    67 NEE-KPVQSPQKLAEEEPTSSEPSSKEALSGSTQQKIFLLKKPQQCDKSDKLTFSSPFKKILNRY 130
            .|| |.:.|.....:..||...|...|               |:  |..|:|...      |...
  Rat   479 PEEAKDLNSCSTKGDCSPTDLRPKQLE---------------PE--DSEDELGDG------LEDS 520

  Fly   131 SSSDTSISSEGEEPANS----SENKSRVLKTSQNAINIKLATDLSNESGYESIAPAKTIS----- 186
            .|.|.:...||:...:|    |.::| |...|:|.::: ::..:||..  :.:.||...|
  Rat   521 CSHDENEEEEGDSECSSLSVVSPSES-VAIISRNCVDL-MSKSISNHE--KVVRPALIYSLFPNV 581

  Fly   187 NTEVIEEDQEETSEDDAECGINMPASKLKITYKFHQTETKLLRKLFNVHGLTEVQGENNNFNLLW 251
            :..:....::|..|       .:|..:.::......|.|..:.|........::...|:::...|
  Rat   582 SPTIYFGTRDERVE-------KLPWEQRRLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCW 639

  Fly   252 TGVHMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRD 316
             |.|||....|::..:|::||||.|:::.|||||::|:.|||...|.|.|...||:|:||.:|:.
  Rat   640 -GHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDSKL 703

  Fly   317 LVVA-HNKHRGPWIVKPAASSRGRGIFIVNSPDQIPQDEQAVVSKYIVDPLCIDGHKCDLRVYVL 380
            |..| .:..|..|||||.||:||.||.:::...|:|:....:|.:|:..|..|.|.|.|||:||.
  Rat   704 LRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVY 768

  Fly   381 VTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCMHLCNYSINKYHSDYIRSSDAQDEDVGHKW 445
            |||:|||.|||:.:|:||.|:.||.....:|.|..|||.|||:||.:::|..::| :....||||
  Rat   769 VTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNAEYQANAD-ETACQGHKW 832

  Fly   446 TLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLACAQSIISACRMFVPNGNNCFELYGFDILIDNA 510
            .|.||..:|..:..::..:...|:|:::|.:::....:.:..:::|....:|.||:||||::|..
  Rat   833 ALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDEN 897

  Fly   511 LKPWLLEINLSPSMGVDSPLDTKVKSCLMADLLTCVGIPAYSPEMKSHYDQKWSRFRSSSCQRIA 575
            ||||:||:|:|||:..:||||..:|..::.|||...|.  ..|.|:.....  |...|||.....
  Rat   898 LKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGF--VLPNMEDILSS--SSSPSSSSGSST 958

  Fly   576 TFPS-------------TSQKTKKS---KKK-------GAAINLNLTGEEQRILRNARLQYSRRG 617
            :.||             |:||.||:   .:|       .:.::: ||.::.|:|.....::||||
  Rat   959 SLPSSPREKCQMTPEHFTAQKMKKAYYLTQKVPDQDFYSSVLDV-LTPDDVRVLVEMEDEFSRRG 1022

  Fly   618 GFVRIFPTDDSMQRYGNFLDSANGIPISTPNVQSQTFQTPIIQHNYNQMLHQN 670
            .|.||||:..| .||..|.:            |.:.|.  |:...:.|..|.|
  Rat  1023 QFERIFPSRIS-SRYLRFFE------------QPRYFN--ILTTQWEQKYHGN 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL5	NP_733081.1	TTL	266..549	CDD:397308	117/283 (41%)
Ttll4	NP_001414011.1	None