Protein Alignment TTLL5 and TTLL4B

DIOPT Version :10

• Sequence 1: NP_733081.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Alignment Length: 903
• Identity: 231/903 - (25%)
• Similarity: 360/903 - (39%)
• Gaps: 279/903 - (30%)

  Fly    29 KLGSREAVLVFRTNILNPKIRKTLSEKSSAQVLTDTKDNEE--KPVQSPQKLAEEEPTSSEPSSK 91
            |:|::.  ::.|....|....|..:..|:..|:.::....|  |.||...|.|.||..:...:..
  Fly   161 KVGAQR--IIIRGTPPNSSTPKVAATPSNVPVVANSVLQSEPYKKVQMLLKRAREEAFAKHTAGN 223

  Fly    92 EALSG-----STQQKIFLLKKP---QQCDKSDKLTFSSPFKKILNRYSSSDTSISSEGEEPANSS 148
            .|.:|     |........|.|   ..|..:..|..|.|.|.::|.:..|....:.:.||
  Fly   224 SAANGNGPKRSAHSPPIQAKVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEE----- 283

  Fly   149 ENKSRVLKTSQNAINIKLATDLSNE----------------------SGYESIA----------- 180
              |||:|  :||.:....||.|...                      ||.:.:|
  Fly   284 --KSRLL--TQNGLTKSAATALETSLYASLYANAPQNSQPQFHSPRISGGDHVASYVGVSLNKGA 344

  Fly   181 -----------PAKTI--------SNTE--------VIEEDQEETSED----------------- 201
                       |...|        |::|        .:|||..||.:.
  Fly   345 GHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLPQKTPSKESVR 409

  Fly   202 --DAEC------------------------------GINMPASKLKI-TYKFHQTETKLLRKLFN 233
              |:|.                              |..|||:..:: .:|......|:::::.
  Fly   410 TTDSEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKWKLSPVMPKIVKRVV- 473

  Fly   234 VHGLTEVQGENNNFNLL-----WTGV---HMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIE 290
                     .|:.|.::     |..|   |||....|.:..:|:.||.|.|:.:.|||.::::|.
  Fly   474 ---------LNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIY 529

  Fly   291 RMQHLRGMKHFDIVPQTFVLP--IESRDLVVAHNKHR-GPWIVKPAASSRGRGIFIVNSPDQIPQ 352
            ......|.|.|..:.:::::|  :||...|...|..: ..|||||.||:||.||.|||...|.|:
  Fly   530 NNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPK 594

  Fly   353 DEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCMH 417
            |...||.|||..||.|:.:|.|:|:||::||.:||.||:|::|:.|.|:|||.....||...|||
  Fly   595 DRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMH 659

  Fly   418 LCNYSINKYHSDYIRSSDAQDEDV----GHKWTLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLA 478
            |.||||||:..:|     |::||.    ||||||.:|...|:.:..:|::|...:.:|:||.:::
  Fly   660 LTNYSINKFSQNY-----AKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVS 719

  Fly   479 CAQSIISACRMFVPNGN---NCFELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLM- 539
             .:|.::  ||:..|.|   |||||:|||:|:|..|.|||||||:|||:..:.|||..||..|:
  Fly   720 -GESGLN--RMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQ 781

  Fly   540 -------------------ADLL-----------------TCVGIPAYSPEMKSH--YDQKWSRF 566
                               ||:|                 ||:    .:.|::.|  |..:...|
  Fly   782 AVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKRIFTTCL----TAEEVRKHNQYTNRSIEF 842

  Fly   567 RSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRRGGFVRIFPTDDSMQR 631
            |......|..                    ||..::.|.|..|..:.:|.....|||||..: ..
  Fly   843 REEYVDTILD--------------------NLLPDDVRCLIVAEDELARCQPLERIFPTAGT-HV 886

  Fly   632 YGNFLDSANGIPISTPNVQSQTFQTPIIQHNYNQMLH--QNLYSKDGRQKQDDNNE-----ADRI 689
            |..::::|                     ..||::|.  :..|:|        |.|     ..|.
  Fly   887 YLRYVENA---------------------RYYNRLLDAWETKYAK--------NREMGIALLSRY 922

  Fly   690 WQYERALETDSEIPFVKKPTVEKCEVEGRRLRK-----------IMLKKISNGSELTP 736
            .:.:..|:. |:....|:|.|...|::...:||           |:...:..|.|:.|
  Fly   923 CRDKYHLQV-SDAAMEKEPNVALTEIDMLHVRKDEVLDGATTLAILKPVVQEGCEVAP 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL5	NP_733081.1	TTL	266..549	CDD:397308	126/329 (38%)
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	121/301 (40%)