Protein Alignment TTLL5 and Ttll5

DIOPT Version :10

• Sequence 1: NP_733081.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_006516052.1
• Gene: Ttll5 / 320244
• MGIID: 2443657
• Length: 1337
• Species: Mus musculus
• Alignment Length: 842
• Identity: 286/842 - (33%)
• Similarity: 441/842 - (52%)
• Gaps: 160/842 - (19%)

  Fly   142 EEPANSSENKSRVLKTSQNAINIKLATDLSNESGYESI--------APAKTISNTEVIEEDQEET 198
            ||.|:|||::                 ||:|:..:..|        .|........::.:|.
Mouse    10 EETASSSEDE-----------------DLANQEDHPCIMWTGGCRRIPVLVFHAEAILTKDN--- 54

  Fly   199 SEDDAECGINMPASKLKITYKFHQTETKLLRKLFNVHGLTEVQGENNNFNLLWTGVHMKLDIVRN 263
                   .|.:...:..::||..:|:::|:|.:...||..||...:.::||:|||.|:|..::|.
Mouse    55 -------NIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRT 112

  Fly   264 LAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRDLVVAHNKHRGPW 328
            |:..|:|||||||||:||||||||||.||||..|.|.|.|:||||:||.|..:...:::|.||||
Mouse   113 LSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPW 177

  Fly   329 IVKPAASSRGRGIFIVNSPDQIPQDEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYE 393
            ||||.|||||||::::|:|:||..:|..:||:||.:||.||..|.|:|:||||||:|||:|||||
Mouse   178 IVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYE 242

  Fly   394 EGIVRLATVKYDRHADNLWNPCMHLCNYSINKYHSDYIRSSDAQDEDVGHKWTLSALLRHLKLQS 458
            ||:.|.|||:||:.:.|:.|..|||.|||:||...||:...|.:.||.|:||::||:||:||.:.
Mouse   243 EGLARFATVRYDQGSKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEG 307

  Fly   459 CDTRQLMLNIEDLIIKAVLACAQSIISACRMFVPNGNNCFELYGFDILIDNALKPWLLEINLSPS 523
            .||..||.::||||||.:::...:|.:||:.|||:.::||||||||:||||.|||||||:|||||
Mouse   308 KDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDNTLKPWLLEVNLSPS 372

  Fly   524 MGVDSPLDTKVKSCLMADLLTCVGIPAYSPEMKSHYDQKWSRFRSS------SCQRIATFPST-- 580
            :..|:|||.|:|:.:::|:.|.||.....|..::.....:..|.||      ..||.....::
Mouse   373 LACDAPLDLKIKASMISDMFTVVGFVCQDPAQRTSNRSIYPSFESSRRNPFQKPQRTRPLSASDA 437

  Fly   581 -------SQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRRGGFVRIFPTDDSMQRYGNFLD- 637
                   |.:.|...|.|.:: |.|:.||.::||..:.:..|||||:|||||.::.:.||::|:
Mouse   438 EMKNLVASAREKVPGKLGGSV-LGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEH 501

  Fly   638 --SAN-----------GIP---ISTPNVQSQTFQTP---IIQHNYNQMLHQNLYS---------- 673
              |.|           |.|   :.|...:..|...|   :...|....||..||.
Mouse   502 KTSMNYMLATRLFQDRGNPRRSLLTGRARVSTEGAPELKVESMNSKAKLHAALYERKLLSLEVRK 566

  Fly   674 ---KDGRQKQ------------------------------DDNNEADRIWQYERALET-DSEIPF 704
               :.||.:.                              |:::|.....|.|.|... :::..:
Mouse   567 RRRRSGRLRAMRPKYPVIAQPAEMNIKTETESEEEEEVGLDNDDEEQEASQEESAGSLGENQAKY 631

  Fly   705 VKKPTV---------------------EKCEVEGRRLR-KIMLKKI--SNGSELTPFQARQTFSM 745
            ....||                     ..|::|.:... |..|.:|  .||: |:..|||..||.
Mouse   632 TPSLTVIVENSPRDNAMKVAEWTNKGEPCCKIEAQEPESKFNLMQILQDNGN-LSKVQARLAFSA 695

  Fly   746 YLESVLRRLTED------------PKDNHEKIILKFLNKFGGSVKPPVMFRNMQTIKVASKARSA 798
            ||:.|..|||:|            .:|...:::::||.:...:::..:.. .:.:.::|...|..
Mouse   696 YLQHVQIRLTKDSGGQTLSPSWAAKEDEQMELVVRFLKRASSNLQHSLRM-VLPSRRLALLERRR 759

  Fly   799 MVAKLLGDFLENYKRDTEAYVDSFDHFGM-------IPSSAYNQFLMHAQESDLEAVLTLHT 853
            ::|..||||:..|.::||...:......:       :.:.::.:|:..|.|::||.|||.:|
Mouse   760 ILAHQLGDFIGVYNKETEQMAEKKSKKKLEEEEEDGVNAESFQEFIRQASEAELEEVLTFYT 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL5	NP_733081.1	TTL	266..549	CDD:397308	163/282 (58%)
Ttll5	XP_006516052.1	TTL	117..395	CDD:397308	161/277 (58%)