Protein Alignment TTLL5 and ttll4

DIOPT Version :10

• Sequence 1: NP_733081.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_002933990.3
• Gene: ttll4 / 100144652
• XenbaseID: XB-GENE-492394
• Length: 1103
• Species: Xenopus tropicalis
• Alignment Length: 705
• Identity: 210/705 - (29%)
• Similarity: 332/705 - (47%)
• Gaps: 130/705 - (18%)

  Fly     2 PSSLCEALTNSSISFDYQKEDDWITSGKLGSREA---VLVFRTNILNPKIRKTLSEKSSAQVLTD 63
            |.:.||:.:..|:.....|.:..:.  ::|:...   :.|..|.|....:.:|...|       |
 Frog   390 PGASCESNSCPSLYTLAPKSESHLP--EIGNNVQGVNITVMATQISTIHLNRTSGAK-------D 445

  Fly    64 TKDNEEKPVQSPQKLAEEEPTSSEPSSKEALSGSTQQKIFLLKKPQQCDKSDKLTFSSPFKKILN 128
            |:...|:....|..:..:|           |.|..::      .|...|
 Frog   446 TQAQPERIDDLPSPVPNQE-----------LDGIEEE------LPDDLD---------------- 477

  Fly   129 RYSSSDTSISSEGEEPANSSENKSRVLKTSQNAINIKLATDLSNESGYESIAPAKTISNTEVIEE 193
                 |:.:..|.|:..:|:.::|       ::|.|..|              |.:.||...|:|
 Frog   478 -----DSEVEEEEEDDEDSNVDQS-------SSIGIPSA--------------ASSFSNARQIDE 516

  Fly   194 DQEE-TSEDDAECGINMPASKLKITYKFHQT----------------ETKLLR-KLFNV------ 234
            ..|: :||.|...   .||....:....|.|                :.|||: |:.||
 Frog   517 SVEQMSSEMDYTV---KPAFSKSLFPNVHPTLYFGTQEEKVELLPWAQRKLLKWKMSNVTPNVVK 578

  Fly   235 HGLT----EVQGENNNFNLLWTGVHMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHL 295
            |.:.    .|..:|.::...| |.|||....::|..||::||||.|:::.|||||::|:.:||..
 Frog   579 HTIARSHFRVTKKNQDWLGCW-GHHMKSTAFKSLRAYQKLNHFPGSFQIGRKDRLWRNLSKMQAH 642

  Fly   296 RGMKHFDIVPQTFVLPIESRDLVVAHNK--HRGPWIVKPAASSRGRGIFIVNSPDQIPQDEQAVV 358
            .|.|.|:..||:||||.:.:.|..|..:  :|..|||||.||:||.||.:::...|:|:....:|
 Frog   643 YGKKEFNFFPQSFVLPQDIKLLKKAWEEGGNRQKWIVKPPASARGMGIQVIHKWSQLPKKRPLLV 707

  Fly   359 SKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCMHLCNYSI 423
            .:|:..|..|.|.|.|||:||.|||||||.||::.:|:||.|:.||.....:|.|..|||.|||:
 Frog   708 QRYLHKPYLISGSKFDLRIYVYVTSFDPLRIYMFTDGLVRFASCKYSSSMKSLGNKFMHLTNYSV 772

  Fly   424 NKYHSDYIRSSDAQDEDVGHKWTLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLACAQSIISACR 488
            ||.::||..:.| |....||||.|.||..:|..:..::.::...|:|::||.::|....:.|..:
 Frog   773 NKNNADYQANPD-QTACQGHKWALKALWNYLNQKGFNSDRIWEKIKDIVIKTIIASDPYVNSFVK 836

  Fly   489 MFVPNGNNCFELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLMADLLTCVG--IPA- 550
            |:|.:...|.||:||||::|..||||:||:|:|||:..:||||..:|..::.|||...|  :|:
 Frog   837 MYVQSPYCCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPSK 901

  Fly   551 -----YSPEMKSHYDQKWSRFRSSSCQRIATFPSTSQKTKKS---------KKKGAAINLNLTGE 601
                 .||...|..:....:.:..|.:.:|     .:|.|::         |...|.:..:||.|
 Frog   902 DEVCTASPSGSSISESSAGKDKGHSLEIVA-----EEKMKRARYLIQKIPDKDLYATVLDHLTPE 961

  Fly   602 EQRILRNARLQYSRRGGFVRIFPTDDSMQRYGNFLDSANGIPISTPNVQSQTFQT 656
            :.|:|.....:.||.|.|.||||:..: .||..|.:....:.|.| |...|.:.|
 Frog   962 DVRVLVETEDELSRCGQFERIFPSPIT-SRYLRFFEQPRYLNILT-NQWEQKYYT 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL5	NP_733081.1	TTL	266..549	CDD:397308	123/286 (43%)
ttll4	XP_002933990.3	TTL	612..905	CDD:397308	124/293 (42%)