Protein Alignment Nepl16 and Nep5

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 951
• Identity: 178/951 - (18%)
• Similarity: 321/951 - (33%)
• Gaps: 328/951 - (34%)

  Fly    12 RKNGVAGLGN---NGHGRNLIT-TANPSGGSSASLLQKQLSFKTPVGSKQMGKSDEIEMIDSANI 72
            |.|| :|.||   ||||:|..| :||          .|||.:: |:               |.|:
  Fly    48 RANG-SGNGNATANGHGQNSATESAN----------GKQLPYE-PI---------------SPNL 85

  Fly    73 ENFNTRYNKNSIIGWICCAPCIWLRTSAAVHKMAITSATLLVTTLLVASPILFLISTAPSPLPRD 137
            ....:::.:                  :..||:.:.....||..||:|..::.|
  Fly    86 IGIQSKFRR------------------SYYHKVVLGGLLALVIILLIAIIVISL----------- 121

  Fly   138 CYMDGDRCSPAVSAPPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC--WRN--------TPN 192
                |.:.|.::     |....|...|:|:...::...|||.:|.:|:|  |.|        |.|
  Fly   122 ----GLKKSSSI-----CRSKECLRTAASLIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSN 177

  Fly   193 -------KNITNLIE---MGNSQKS---------------VDSQML----------YLFQ----- 217
                   .:|..::.   ..|..||               :|:::|          ||.:
  Fly   178 DWFRERQAHIMRVVREFLRSNITKSEPEAVGKAKTMYRACMDTKLLDKRDLEPLINYLLRFGLPV 242

  Fly   218 ------------NKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLI 270
                        :|....:..:.:|..:|.:     |...|...|.:.|:    .|.|......|
  Fly   243 LPSALNLTLGSGSKYATEAANVKYNWLQSIV-----SIKQHLTMDLIIGF----DVFPDPFNRTI 298

  Fly   271 AKIYDLGPSPLVD----LYHDLSYG--RRPHILLII----------------------SGPSTSS 307
            .:| .|| :|..|    ..:|.|:.  |:.|...|.                      ...||..
  Fly   299 NRI-ALG-TPETDSAFPFNNDDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGM 361

  Fly   308 T--------ILERKIRWMSPKAPPSRIRQGVPKLLADLIENFLPYFVSYAQRVSEKDTIFEFIKD 364
            |        ::|:.:.::.|.........|:.:|            |....||:.|  :.||.::
  Fly   362 TAYLHYVRKVIEKYLLYVDPNVNQEEATLGITEL------------VKQGVRVARK--VHEFKEE 412

  Fly   365 LNKLQVEHSRRGFWDSTVLYNVSSLQD---------LYPVLNW---------------TLLIPQN 405
            ...:........  |..|...:..||:         ..|:  |               .:.:.||
  Fly   413 AENMTKPSKNPA--DDIVYITLQDLQNQTDKNIAPKTLPI--WVRYMELILKGTRHAGNIQMTQN 473

  Fly   406 WSGPIVVRNSD--YLK-ALEY-------------FLTKYPTRVAHNSLLLLSALQILPRDYP--- 451
            .:  |:...:|  ||: .:||             ||:.....|.|.|    |::::|..:|.
  Fly   474 LT--IITSQADITYLQNIVEYLDDTPASHIESYLFLSTIEELVLHTS----SSMRLLHSEYMRVA 532

  Fly   452 -SPEVCTRSTMWALPELSSSL-----YI---AQHSSEDLKDTTKRAEIIFKSLKAHLKRAPSLKG 507
             ..|..|..:::....::|.|     |:   |..:.|.|....:....|.:|....:|....:..
  Fly   533 IGTEGSTPRSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDA 597

  Fly   508 AALVKLSALKIQSQTWEGF----SNTTDLLKSLQPLNITSECWFQNILEIY------KKNKLE-P 561
            |...|......:.:::.||    .|.:.|....:...:.:....:|:::..      |.|::: |
  Fly   598 ATKRKTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKP 662

  Fly   562 NDISLNGGSHDAWA-YPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEIL 625
            ..|        .|| .|.....|:...|::|.||::::..|:::..|.. |:|.|:|..:..|
  Fly   663 EPI--------GWATSPSNVNAFHTFQSNAITVPIAILQYPFYDLGLEA-LNYGSIGTILGHE-- 716

  Fly   626 RSITKSFDEKAMR------------------------CVPHSVNIFSNYSRMDI----------- 655
              :|..||:...|                        |.   |..:|.|...||
  Fly   717 --LTHGFDDSGRRFDRAGNMVEWWSNRTIDEYVNRTECF---VEQYSRYHLADIDEYIDGELTLG 776

  Fly   656 --LIHSGGMQISYHSMLSLTGPI-KGMARLPGL-NLTPTQIFFLVSAQELC-----AESNYLGID 711
              :..:|||:.::::.......: :..::|||| :.:..|:||:......|     |.|.|...|
  Fly   777 ENIADNGGMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTPAASRYALTD 841

  Fly   712 TNAPEFDNILGWLVAQGGSATEVFKCPSGSMINV-QKTCNV 751
            ::.|....:.| :::........|||..|:.:|. |..|.:
  Fly   842 SHCPGQMRLRG-VLSNSEEFARTFKCARGTPMNPDQPKCRI 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	143/779 (18%)
Nep5	NP_733186.2	PepO	146..882	CDD:226118	144/788 (18%)
		M13	151..880	CDD:189000	143/780 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910