Protein Alignment Nepl16 and Nepl14

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 768
• Identity: 164/768 - (21%)
• Similarity: 275/768 - (35%)
• Gaps: 245/768 - (31%)

  Fly   134 LPRDCYMDGDRCSPAVSAPPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC--WRN--TPNKN 194
            |.::..:.|:...|......:....:..:.|..:.:.:|.:.|||.:|..::|  |::  ||.:.
  Fly    19 LQQNALVSGEDLPPPFQRIYQSEQTVRRSKAQDMGSHVNKSIDPCVDFYAYACGNWKSTLTPQQQ 83

  Fly   195 ITNLIEMGNSQKSVDSQMLYLFQNKIMNGSFGILH---NLFESCLQQTTNSTVMHRIF-----DS 251
            :         |:..|.::|.|.:..:......|:.   .||:||:....:.:...:.|     :.
  Fly    84 L---------QQQTDRELLLLVEEAVRREDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQ 139

  Fly   252 LGGYLPVGSVGPSS-----------IAPLIAKIYDLGPSPLVDLYHDLSYGRRPHILLIISGPST 305
            .||:..|    |.|           ::.|.......|...|:.|....:||......|.:|.|||
  Fly   140 NGGFPAV----PGSQWAVHHHDYNWLSVLGGLRLRYGMDILIGLRVGYNYGNVNENSLYLSEPST 200

  Fly   306 SSTILERKIRWMSPKAPPSRIRQGVPKLLADLIENFLPYFVSYAQRVSEK---------DTIFEF 361
                       :.|....:|.|..:...:.:.:|:          ||:.:         |.....
  Fly   201 -----------LIPTELCTRNRSDIRDSIYEPLEH----------RVASELKSWLALGHDESARL 244

  Fly   362 IKDLNKLQVEHSRRG--------FWDSTVLYNVSSLQDLYPVLNWTLLIPQNWSGPI------VV 412
            ..|:  |..||...|        .||:.        :.|| :.|:|....:.:|..|      .|
  Fly   245 AADI--LSFEHELCGGMKGGSFESWDAE--------EQLY-LANYTRKTLREFSNSIELDLDSYV 298

  Fly   413 RNS--------DYLKALEYFLTKYPTRVAHNSLLL--------LSALQILPRDYPS--PEVCTRS 459
            |.|        .|:.|.|||.....|..|||..|:        :|||.....|.|.  ...|...
  Fly   299 RASFGQDIYKPVYMAAPEYFRQLKRTVSAHNISLVANYIMYRAVSALNFPLDDRPQLRKRECLER 363

  Fly   460 TMWALPELSSSLYIAQHSSED-------LKDTTKRAEIIFKSLKAHLKRAPSLKGAALV---KLS 514
            |...||.....||..|..:||       |.||.|.|      |:..|.....::|...|   ||.
  Fly   364 TKELLPTALGELYARQFGTEDGRIDLDNLYDTLKTA------LRQSLGAEWLVEGTQRVGQEKLR 422

  Fly   515 ALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQN------ILEIYKKNKL------EPNDISLN 567
            .||:|..|:|    ...:||    |.:....::||      :::..:.|:|      .|.|
  Fly   423 NLKLQMPTYE----RPVILK----LQLERGNYWQNLRQLLGVVQSQRNNRLFEEFLPAPTD---- 475

  Fly   568 GGSHDAWAYPIVSTIFYDT------LSHSIVVPLSVILIPYFNAVLPPYLH---YASVGVSIAKE 623
                     |:.:   |:.      :...:.:.|:::..|.::   |.|.|   ||::||.:|::
  Fly   476 ---------PVEA---YEARVRLRPVQRRLDMGLALLQPPAYD---PRYGHAIRYATLGVQLAQQ 525

  Fly   624 ILRSITKSFDEKAMRCVPH-SV--------------------NIFS----NYSRMDI------LI 657
            ::    .:||:      || ||                    |.|:    ||.|.::      :.
  Fly   526 LV----MAFDD------PHWSVGLLERDNWDGQTAWQYHIRSNCFARQVDNYLRPNVSATTQLIT 580

  Fly   658 HSGGMQISYHSMLSLTG---PIKGMAR-----LPGLNLTPTQIFFLVSAQELCA-ESNYLGIDTN 713
            .|..:.:::.:.|:..|   |.....:     ||.||.:.|.:|||..|||.|: |......:..
  Fly   581 DSAAINVAFRAYLTWLGFQEPNNDFTKLTKETLPDLNYSNTALFFLAYAQEHCSLEEARPRDEQG 645

  Fly   714 APEFDNILGWLVA--QGGSATEV---------------FKCPSGSMINVQKTC 749
            .||     |:|.:  |..:.|.:               |:||.||.:|....|
  Fly   646 TPE-----GYLYSARQNHTWTRLLVNGPLRNSVEFASEFRCPIGSPMNPASKC 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	159/726 (22%)
Nepl14	NP_651097.1	M13	60..693	CDD:341056	158/725 (22%)