Protein Alignment Nepl16 and nep-24

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 125/683 - (18%)
• Similarity: 229/683 - (33%)
• Gaps: 220/683 - (32%)

  Fly   123 ILFLISTAPSPLPRDCYMDGDRCSPAVSAPPE-----CSDPICEAVASSIQARLNWNKDPCTEFK 182
            :|.|:.|..:||             |:.|...     |:.|.|..:|..:....:.:.|||..|.
 Worm    14 MLLLLLTCTAPL-------------AIGATTPATRNVCNTPACITLAHMLHNYHDPSVDPCDNFH 65

  Fly   183 KFSCWR----------NTPNKNITNLIEMGNSQKSVDSQMLYLFQNKIMNG-SFGILHNLFESCL 236
            :|:|.|          ....|.|.|:::.            :|.:|:.... |...:..|:::|.
 Worm    66 QFACGREHEHETEDIYTKKTKTINNIMKR------------FLKKNETSRSKSENAMRTLYKACK 118

  Fly   237 QQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIAKIYDLGPSPLVD-------------LYHDL 288
            ....|||....                .::..:...|..:|..|:||             |.:.:
 Worm   119 TLEKNSTASRN----------------KALQDIFQDIQSIGAWPVVDDKWDESKFDLNDFLVNLV 167

  Fly   289 SYGRRPHILLIIS----------GP-----------STSSTILERKIRWMSPKAPPSRIRQGVPK 332
            ..||:...|..::          ||           .|.|.||:           .:.::....|
 Worm   168 RLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNVDLGKTISEILK-----------ANSVQTNNKK 221

  Fly   333 LLADLIENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQVEH--SRRGFWDSTVLYNVSSL------ 389
            ||.||.|     :|:..:.:|:        ...|.:|..:  |.|..:.|:|  |.|.|
 Worm   222 LLDDLAE-----YVNLEKALSQ--------HKFNTVQPGYIFSERSDFVSSV--NFSRLVLEMMS 271

  Fly   390 ---QDLYP-------VLNWTLLIPQNWSGPIVVRNSDYLKALEYFLTKY-PTRVAHNSLLLLSAL 443
               :.|:|       :.|.:|...:|.:...::||:.......|.:.|: .|.:|..:
 Worm   272 PDKRTLFPEVYQIMYLTNTSLFFGKNNNLETIIRNTSKRALANYLIFKFIDTSIADLT------- 329

  Fly   444 QILPRDYPSPEV-CTRSTMWALPELS-SSLYIAQHSSEDLKDTTKRAEI----IFKSLKAHLKRA 502
                  |.||.. |.:..:..||..: .:.|....|.|:.|..||..|.    :.|.:.|....:
 Worm   330 ------YGSPSAFCEQKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKIIGATDWMS 388

  Fly   503 PSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQNILEIYKKNK-LEPNDISL 566
            ...|..|:.::|::.:.....:.|.....|....:.||::|...:..:  :.|.|: :...::..
 Worm   389 IKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGLFEHLNLSSSDTYYTV--VRKINRFMREQEMDY 451

  Fly   567 NGGSHDAWAYP----IVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRS 627
            ..|  :...||    :::...|:...:::::.......|:|::..|.|.:.|....::|
 Worm   452 YTG--EVPYYPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLA------ 508

  Fly   628 ITKSFDEKAMRCVPHSVNIFSNYSRMDILIHSGGMQISYHSMLSLTGPIKGMARLPGLNLTPTQI 692
                                          |..|...|.|.|..:||..:       :.|||.:
 Worm   509 ------------------------------HEMGHTFSPHLMDIMTGTTE-------VWLTPKE- 535

  Fly   693 FFLVSAQEL-----CAESNYLGIDTNAPEFDNI 720
                 .:|.     |.|..|...|.  ||:..|
 Worm   536 -----TEEYEKRVKCLEDQYTEYDD--PEYGRI 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	114/625 (18%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	113/624 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000