Protein Alignment Nepl16 and nep-20

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 842
• Identity: 158/842 - (18%)
• Similarity: 297/842 - (35%)
• Gaps: 267/842 - (31%)

  Fly    27 NLITTANPSGGSSASLLQKQLSFKTPVGSKQMGKSDEIEMID-SANIENFNTRYNKNSIIGWICC 90
            |.:..|||...:..::.:|.   |.....|:..|:::....: :|||        |:.||.  |.
 Worm   138 NPVNPANPVIPAKQNMEKKN---KRKEKEKERKKAEKFSADEKTANI--------KDRIIN--CV 189

  Fly    91 APCI-----WLRTSAAVHKMAITSATLLVTTLLVASPILFLISTAPSPLPRDCYMDGDRCSPAVS 150
            .|.|     ||                          :||:               |.|..   .
 Worm   190 YPVILIILFWL--------------------------LLFI---------------GARQD---E 210

  Fly   151 APPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC-----------WRNTPNKNITNLIEMGNS 204
            .|..|..|.|..:|..:.|..:.:...|..|.|.:|           .|:...|.:.
 Worm   211 KPSLCESPQCITLAFELSAYQDTSVSKCHNFYKATCGKYKHHQALDKHRDAKKKEVV-------- 267

  Fly   205 QKSVDSQMLYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPL 269
             |.:..:.|...::.|.:.....:..:|..|.:.:.|.|           ||.:
 Worm   268 -KRIVREFLRRNESSITSKFEPAIRLMFGKCNKFSQNKT-----------YLDI----------- 309

  Fly   270 IAKIYDLGPSPLVDL-YHDLSYGRRPHILLIISGPSTSSTILERKIRWMS----PKAPPSRIRQG 329
            ...|..:||.|::.. :.|:.:....::|.::....|...:.:.:.|.::    |...||..:||
 Worm   310 FKDIEKIGPWPVLKSDWVDVMFNLNDYLLSLVELGFTDFGLFKLEFRQLAFGQFPVIAPSEQKQG 374

  Fly   330 --VPKLLADLIENFLPYFVSYAQRV-SEKDTIFEFIKDLN--KLQVEH-SRRGFWDSTVLYNVSS 388
              :.|::.:::|         |..| :::..:.:::::.:  |.|:.| |..|.....:.||.|:
 Worm   375 NQLEKIILEILE---------ANGVQADRQKLSKYLREYSEFKSQLRHMSLEGTSVKYIRYNAST 430

  Fly   389 L--------QDLYPVLNWTLLIPQNWSGPIVVRNSD-------------------------YLKA 420
            |        |.:.|:...:.|:.:..||.::..:|.                         ::.|
 Worm   431 LSVNISALVQKMAPMSTSSGLVRRIQSGILITNSSSFFGKNLDAIIQQTHKRTLANYLIFHFIDA 495

  Fly   421 LEYFLTKYPTRVAHNSLLLL--SALQILPRDYPSPEVCTRSTMWALPELSSSL------YIAQHS 477
            :.:.||.......|..:.||  .:||:|.:|:...|     ....:.|::..|      .|::.|
 Worm   496 VTFDLTSGAKHSEHTLIDLLPRGSLQVLSQDFVDEE-----DQGVMVEMAKDLKKHVVEMISEGS 555

  Fly   478 SEDLKDTTKRAEIIFKSLKAHLKRAPSLKGAALVKLSALKIQSQTWEGFSNT--TDLLKSLQPL- 539
            |.|      :..::|:. |...|....::...:|....|:|.:|.:|..:.|  ..|.|.:|.|
 Worm   556 SLD------KGHLVFEE-KERRKLIRKVQDILVVTKYPLEILNQNFEKLNLTYSDSLHKIIQKLR 613

  Fly   540 NITSECWFQNILEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFN 604
            ...||    .::| |....|:|.|..:.|.:|            |:..::.:::...:|..|||:
 Worm   614 RFRSE----QLIE-YLGGDLDPTDKGMWGSAH------------YEQATNDLIIIAPIIDGPYFD 661

  Fly   605 AVLPPYLHYASVGVSIAKEILRSITK---SFDEKAMRCVPHSVNIFSNYS--RMD---------- 654
            ...|.|::...:|..|::|:.||:..   ..|||.     |:.|...:.|  |.|
 Worm   662 TSYPNYVNIFFMGFIISRELGRSLDSVRIRKDEKG-----HTENWLKSESLKRFDNNVKCWRKKI 721

  Fly   655 --------ILIHSGGMQISYHSMLSLTGPIKG--MARLPGL-NLTPTQIFFLVSAQELC------ 702
                    :|....|.:.|:.::......:.|  :.::.|. ::|..||||.:.|...|
 Worm   722 TGTRFLNEMLADHVGHEASFMALKKWEKEMNGTIVEKIRGYESMTMEQIFFHLQALYFCRPPGGS 786

  Fly   703 --------AESNYLGIDT-------NAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTC 749
                    |..:|   .|       |.|:|              .:.|.|.|...:|.:..|
 Worm   787 TGELTAKDARQHY---STRVNEAFKNMPQF--------------AKAFGCSSNQNMNSKTKC 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	128/685 (19%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910