Protein Alignment Nepl16 and nep-8

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 699
• Identity: 122/699 - (17%)
• Similarity: 239/699 - (34%)
• Gaps: 249/699 - (35%)

  Fly   155 CSDPICEAVASSIQARLNW---NKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSVDSQMLYLF 216
            |..|.|..::..:   ||:   :.|||.:|.:.||.|........:.::   .:|.:..:.:..|
 Worm    56 CDSPECITLSHEL---LNYQDPSVDPCVDFFQHSCGRFHEQSVSESRLQ---KKKHILRKQIREF 114

  Fly   217 QNKIMNG---SFGILHNLFESC--LQQTTNST------VMHRIFD---SLGGYLPVGSVGPSSIA 267
            .:||.|.   |..::..:|:.|  .::|:|..      .:|.:|:   .:|.:
 Worm   115 LHKIQNSTSKSENLMKLVFDKCEASKKTSNDNYKISRDAIHDVFNDIKKIGAW------------ 167

  Fly   268 PLIAKIYDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQG--- 329
            ||:.|.:|.....|.::..:|           :...:|:..:.:...|.::         :|
 Worm   168 PLLDKNWDGSKFDLNEMLSNL-----------VKLGATNLGLFQLDFRILT---------EGKFV 212

  Fly   330 -VPKLLADLIENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQVEHSRRGFWDSTVLYNVSSLQDLY 393
             :...|..::.|  ...:|....:.|.:.:....::::|...|:              ||||
 Worm   213 RIAPTLGSIVHN--STMISMISEILEANGVQPDSEEISKEFEEY--------------SSLQ--- 258

  Fly   394 PVLNWTLLIPQNWSGPIV-----VRNSDYLKALEYFLTKYPTRVAHNSLLLLSALQILPRDYP-- 451
                 ..|.....||.:.     ||:.::...:...:  :|:||:.    :...::::..::|
 Worm   259 -----MKLAKYQSSGKLSISLPGVRSINFSSLITEMI--HPSRVSK----IFGKIRVVTSEHPLF 312

  Fly   452 --------------SPEVCTRSTMWALPELSSSLYIAQ-----HSSEDLKDTTKRAEI-IF---- 492
                          |....|.:.......:.||..|.:     :..:|::....||.: :|
 Worm   313 FKSNETESLDTIIESTSNKTLANFLIFNYIQSSYNIMKGARRGNCEDDVRREFPRASLRVFMRNF 377

  Fly   493 ---------KSLKAHLKR------------APSLKGAALVKLSALKIQ-------------SQTW 523
                     |.|...||:            ||.:|.:.|.|:.|:|:.             .:.:
 Worm   378 VDKGNRDGVKKLTEELKKNTLEMIQDTENLAPPVKESMLKKVEAIKVTIGYPDHFDPPGTLDKEF 442

  Fly   524 EGF--SNTTDLLKSLQPLN----------ITSECWFQNILEIYKKN---KLEPNDISLNGGSHDA 573
            |.|  .:|....:..|.||          |..|.....|.|:.|.|   |...|.:
 Worm   443 ENFDLDSTDSYYRIFQKLNRLRSEQQMEFIAGETPISPIKEVLKVNANYKRSKNAL--------- 498

  Fly   574 WAYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKS---FDE- 634
                   |:|...|..           |:|:...|.|::....|..||.||..|:..:   :||
 Worm   499 -------TVFAPFLDD-----------PFFDITYPDYVNLFFSGFLIAHEIGHSVDANGLGYDEN 545

  Fly   635 ----------------KAMRCVPHSVNIFSNY-------------SRMDILIHSGGMQISYHS-- 668
                            |..:|:   |:.:.||             |..:|:....|.::::.:
 Worm   546 GKPMDGIRLEHVTEYGKQGQCL---VDQYDNYDDPVYGKKMNGTHSINEIIADWVGHEVTWRAYK 607

  Fly   669 ------MLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCAESNYLGID 711
                  ||||.|       |..:|:  .|::|.|.:...|.|.:.:.::
 Worm   608 KMDTSKMLSLIG-------LKDINM--DQLYFRVQSLLFCRERDTISLE 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	117/675 (17%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	117/676 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910